Analytical Services available for Targeted Metabolomics / Lipidomics

The DBT-SAHAJ National Facility at RGCB is in the process of establishing a large number of targeted panels for quantitation of selected groups of metabolites and lipids using mass spectrometry. These targeted panels provide accurate absolute quantitation of a focused group of analytes using available standards.

Targeted metabolomics or lipidomics is a quantitative approach in which a known set of metabolites is quantitated using ¹³C, ²H or ¹⁵N isotope-labeled internal or external reference compounds. The resulting data can then be used as input variables for statistical analysis.

The goal of the facility is to establish a panel of more than 300 lipid molecules/species, which comes under 25 major lipid classes as shown in Table-1.

At present our panels include 311 lipid molecules, which come under 25 lipid classes and 2 metabolites of one carbon metabolism. These panels are being established in our facility to meet the research needs of investigators on a case-by-case basis.

Investigators who are interested in measuring metabolites or lipids not listed in the panel should contact the facility in-charge to discuss the possibilities for establishing a method