Deciphering the impact of ER α-AIRE association during embryo implantation
Recent work from our lab has shown that AIRE is expressed in uterine endometrium during decidualization and in vivo silencing of Aire results in implantation failure. Also that AIRE migrates into the nucleus via DOCK180 under estrogen and progesterone treatments (Soumya et al 2016; Mohan JJ et al 2018). AIRE was also proved to be an interacting partner of estrogen receptor. This project aims to gain structural insights of ER α-AIRE interaction and its impact on modulating events associated with embryo implantation.
Betcy Susan Johnson
Evaluation of circadian rhythm in pathophysiology of Polycystic Ovary Syndrome (PCOS).
Lipika Priyadarsini Patra
Understanding mechanism of Treg Regulation in PCOS
SERB-Junior Research Fellow
Decoding the modalities in regulating embryo adhesion during implantation
Rajiv Gandhi Centre for Biotechnology (RGCB), Thycaud Post,
Poojappura, Thiruvananthapuram - 695 014, Kerala, India +91-471-2529400
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