Publication - 2025

Publication - 2025

1. Kundu A, Bera P, Mishra S, Vadassery J. Deep metabolomics revealed trajectories of jasmonate signaling-mediated primary metabolism in Arabidopsis upon Spodoptera litura herbivory. Physiol Plant. 2025 Jan-Feb;177(1):e70035. doi: 10.1111/ppl.70035. PMID: 39775752.
2. Chaudhary S, Siddiqui JA, Pothuraju R, Bhatia R. Ribosome biogenesis, altered metabolism and ribotoxic stress response in pancreatic ductal adenocarcinoma tumor microenvironment. Cancer Lett. 2025 Mar 1;612:217484. doi: 10.1016/j.canlet.2025.217484. Epub 2025 Jan 20. PMID: 39842499.
3. V. Amrutha, Kanakangi S. Nair, Chandrabhas Narayana, Harish C. Barshilia. Fabrication and performance evaluation of a highly stable micro/nanostructured surface using rapid thermal treatment of Si-coated stainless steel for solar thermal applications. Journal of Alloys and Compoundshttps://doi.org/10.1016/j.jallcom.2024.178093
4. Tiwari SK, Chandrasekharan A, Lupitha SS, Mathew KA, Jancy SV, Halikar AM, Sanjeev VS, Sivakumar KC, Prasad T, Anurup KG, Rather AA, Tiffee P J J, Jayaprasad AG, Sivasailam A, Santhoshkumar TR. HYPOXIA INDUCED MITOPHAGY GENERATES REVERSIBLE METABOLIC AND REDOX HETEROGENEITY WITH TRANSIENT CELL DEATH SWITCH DRIVING TUMORIGENESIS. Free Radic Biol Med. 2025 Feb 11:S0891-5849(25)00082-6. doi: 10.1016/j.freeradbiomed.2025.02.007. Epub ahead of print. PMID: 39947492.
5. Pillai VS, Ravindran S, Krishna G, Abhinand CS, Nelson-Sathi S, Veettil MV. REST Is Restless in Neuronal and Non-Neuronal Virus Infections: An In Silico Analysis-Based Perspective. Viruses. 2025 Feb 8;17(2):234. doi: 10.3390/v17020234. PMID: 40006989; PMCID: PMC11860772.
6. Ngashangva L, Martin S. Organ-on-chip for advancing CAR therapy. Clin Transl Immunology. 2025 Feb 26;14(2):e70024. doi: 10.1002/cti2.70024. PMID: 40018376; PMCID: PMC11862890.
7. Feba Shaji, Jamshaid Ali, Rakesh S. Laishram. Cleavage site heterogeneity at the pre-mRNA 3'-untranslated region regulates gene expression in oxidative stress response. Redox Biology 24 February 2025 | https://doi.org/10.1016/j.redox.2025.103565
8. Ketul Saharan, Somanath Baral, Surajit Gandhi, Ajit Kumar Singh, Sourav Ghosh, Rahul Das, Viswanathan Arun Nagaraj, Dileep Vasudevan. Structure-function studies of a nucleoplasmin isoform from Plasmodium falciparum. Journal of Biological Chemistry https://doi.org/10.1016/j.jbc.2025.108379
9. Surendran A, Zhang H, Stamenkovic A, Ravandi A. Lipidomics and cardiovascular disease. Biochim Biophys Acta Mol Basis Dis. 2025 Mar 22;1871(5):167806. doi: 10.1016/j.bbadis.2025.167806. Epub ahead of print. PMID: 40122185.
10. Vadakkath Meera, Suresh Surya, Surendran Parvathy, Nair Pradeep Jyothi, Paul Ann Riya, Biju Surendran Nair, Jackson James,Notch1 is essential for maintaining adult SVZ neurogenic niche and its knockout leads to aberrant neurogenesis and fine olfactory dysfunction,Gene Reports,Volume 39,2025,102200,ISSN 2452-0144,https://doi.org/10.1016/j.genrep.2025.102200.
11. Mishra SR, Modak A, Awasthi M, Sobha A, Sreekumar E. Ponatinib and other clinically approved inhibitors of Src and Rho-A kinases abrogate dengue virus serotype 2- induced endothelial permeability. Virulence. 2025 Dec;16(1):2489751. doi: 10.1080/21505594.2025.2489751. Epub 2025 Apr 6. PMID: 40189910.
12. Mishra V, Mitra P, Shinde S, Chaudhari S, Deshmukh AS. Neospora caninum in pigs and pig farmers in India: Examining the prevalence, immunodominant antigens and associated risk factors. Microb Pathog. 2025 Mar;200:107352. doi: 10.1016/j.micpath.2025.107352. Epub 2025 Jan 31. PMID: 39894235.
13. Venkatachalam S, Christyraj JRSS, Christyraj JDS, Subramaniam R, Mathews MGR, Anandharaj JL, Venkatachalam K, Kalimuthu K, Yesudhason BV. Exploring the Fluorescence Bioactive Compounds in the Coelomic Fluid of Earthworms: Insights into Their Structural, Spectroscopic, and Functional Properties for Biomedical Applications. J Oleo Sci. 2025;74(2):203-220. doi: 10.5650/jos.ess24168. PMID: 39880640.
14. R. Santhoshkumar; A. Hima Parvathy & E. V. Soniya. Modifications in Metabolomic Profile of Andrographis paniculata by Arsenic Tolerance Herbaspirillum sp.: Perception into Plant–Microbe Interactions. Journal of Plant Growth Regulation https://doi.org/10.1007/s00344-025-11639-1
15. Bonizzi A, Signati L, Grimaldi M, Truffi M, Piccotti F, Gagliardi S, Dotti G, Mazzucchelli S, Albasini S, Cazzola R, Bhowmik D, Narayana C, Corsi F, Morasso C. Exploring breast cancer-related biochemical changes in circulating extracellular vesicles using Raman spectroscopy. Biosens Bioelectron. 2025 Jun 15;278:117287. doi: 10.1016/j.bios.2025.117287. Epub 2025 Feb 19. PMID: 40023908.
16. Chandran M, Rameshkumar KB, Jaleel A, Ayyappan JP. Embelin Elevates Endoplasmic Reticulum Calcium Levels and Blocks the Sterol Regulatory Element-Binding Protein 2 Mediated Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Improves the Low-Density Lipoprotein Receptor Mediated Lipid Clearance on Hepatocytes. Chem Biol Drug Des. 2025 Feb;105(2):e70055. doi: 10.1111/cbdd.70055. PMID: 39902651.
17. Remya Reveendran, Sara Jones, Rajesh Chandramohanadas, Sreelathakumari Krishnan Thankam & Suchithra Tharamel Vasu. Vitamin D levels in diabetic foot ulcer patients: a meta-analysis and systematic review. International Journal of Diabetes in Developing Countries https://doi.org/10.1007/s13410-025-01480-3
18. Himadri Mandal, Saptarshijyoti Gogoi, Atheena Menon G, Malini Laloraya, Bornali Gogoi, Satya Sundar Bhattacharya. Crosstalk between gut metabolomics, bioaccumulation, and microbial enrichment in earthworms for effective remediation of toxic metals: Insights from green waste-based vermicomposting systems. Journal of Environmental Management https://doi.org/10.1016/j.jenvman.2025.125430
19. Nikhil Bharambe, Ketul Saharan, Dileep Vasudevan, Sandip Basak. 2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53. Journal of Structural Biology. 108203. https://doi.org/10.1016/j.jsb.2025.108203
20. Retnakumar RJ, Chettri P, Lamtha SC, Sivakumar KC, Dutta P, Sen P, Biswas S, Agarwal N, Nath AN, Devi TB, Thapa N, Tamang JP, Chattopadhyay S. Genome-wide accumulations of non-random adaptive point mutations drive westward evolution of Helicobacter pylori. BMC Microbiol. 2025 Apr 22;25(1):229. doi: 10.1186/s12866-025-03944-2. PMID: 40263995.
21. Lupitha SS, Varghese GR, Das LJ, Prabhakaran P, Ananda AM, Mani RS, Sreekumar E. Assessing anti-rabies vaccine response in humans: A rapid and high-throughput adaptable, pseudovirus-based neutralization assay as an alternative to rapid fluorescent focus inhibition test (RFFIT). PLoS Negl Trop Dis. 2025 Apr 10;19(4):e0013010. doi: 10.1371/journal.pntd.0013010. PMID: 40208858; PMCID: PMC12013880.
22. Jyothy A, Hussain J, S SC, Chandraprabha VR, Nair MG, Vasudevan S, Sreedharan H, Abraham B, Maliekal TT, Natarajan K, Sengupta S. a-Fodrin-CENP-E interaction is critical for pancreatic cancer progression and drug response. Cell Cycle. 2025 Apr 10:1-25. doi: 10.1080/15384101.2025.2485837. Epub ahead of print. PMID: 40211684.
23. Jobichen C, Saharan K, Samal A, Choong YK, Jagdev MK, Mohapatra C, Jian S, Babbar R, Dobson RCJ, Grover A, Vasudevan D, Sivaraman J. Cryo-EM structure provides insights into the unusual heptameric assembly of rice (Oryza sativa L.) ClpB1 AAA+ ATPase. Int J Biol Macromol. 2025 May 3:143917. doi: 10.1016/j.ijbiomac.2025.143917. Epub ahead of print. PMID: 40324502.
24. Sk S, Majumdar BB, Vikraman D, Mahanta K, Soman A, Rajavelu A, Mondal J, Mahendran KR. A Dynamic Sugar-Selective Bacterial Nanopore for Targeted Antibiotic Transport. Small. 2025 May 6:e2502110. doi: 10.1002/smll.202502110. Epub ahead of print. PMID: 40326190.
25. Singh SK, Sudhir S, Menon V, Warrier AR, V AR, Edathadathil F, Sathyapalan DT, Ps S, Thomas S. Epidemiology and clinical outcomes of monomicrobial carbapenem-resistant Enterobacteriaceae (CRE) from a metropolitan area of Kerala, India. J Infect Dev Ctries. 2025 Apr 29;19(4):569-575. doi: 10.3855/jidc.18777. PMID: 40305539.
26. Paul M, Thomas S. Detection of morphological variants of colistin-resistant Klebsiella pneumoniae associated with sepsis in Kerala, India. Acta Microbiol Immunol Hung. 2025 Mar 20;72(1):39-42. doi: 10.1556/030.2025.02515. PMID: 40111416.
27. Anitha A, Banerjee M, Thanseem I, Melempatt N, Prakash A, Iype M, Thomas SV. Whole Exome Sequencing Study of a Multizygotic Quadruplet Discordant for Autism Spectrum Disorder Reveals Novel Autism Candidate Genes. Neurol India. 2025 Jan 1;73(1):152-155. doi: 10.4103/neurol-india.Neurol-India-D-24-00651. Epub 2025 Feb 7. PMID: 40652485.
28. Niitsu A, Thomson AR, Scott AJ, Sengel JT, Jung J, Mahendran KR, Sodeoka M, Bayley H, Sugita Y, Woolfson DN, Wallace MI. Rational Design Principles for De Novo a-Helical Peptide Barrels with Dynamic Conductive Channels. J Am Chem Soc. 2025 Apr 9;147(14):11741-11753. doi: 10.1021/jacs.4c13933. Epub 2025 Mar 28. PMID: 40152328.
29. Kalimuthu Kalishwaralal; A. Abhishek; Sachin Sharma; M. A. Firer. Selecting Peptides for Targeted Delivery of Drugs Inside Cancer Cells. International Journal of Peptide Research and Therapeutics doi.org/10.1007/s10989-025-10712-3
30. Anju Mathew; Ann Mary Alex; Chathathayil Mohammedali Shafeeque; Saboora Beegum Muthubeevi; Vijayakumar Krishnapillai; Moinak Banerjee . Genetic predictors of attempted suicide among South Indian adolescents and young adults: A case-control study Biomarkers in Neuropsychiatry doi.org/10.1016/j.bionps.2025.100126
31. O'Sullivan FLA, Das AV, Rojas-Rios P. Editorial: Functional implications of Piwi proteins and piRNAs in stem cell maintenance and development. Front Cell Dev Biol. 2025 Mar 17;13:1583955. doi: 10.3389/fcell.2025.1583955. PMID: 40166634; PMCID: PMC11955655.
32. Das DJ, Jaikumar VS, Suryaletha K, Paul M, Shankar A, Nath SR, Thomas S. Probiotic Lacticaseibacillus paracasei from human gut microbiome against colistin-resistant Klebsiella pneumoniae: in vitro, in vivo and probiogenomic approaches. Benef Microbes. 2025 Apr 9:1-21. doi: 10.1163/18762891-bja00065. Epub ahead of print. PMID: 40312034.
33. Jacob RS, Gunasekaran S, Kumar M, Omkumar RV. Intracortical Injection of Okadaic Acid Increases Locomotor Activity and Decreases Anxiety-like Behaviour in Adult Male Rats: Potential Involvement of NMDA Receptor. Ann Neurosci. 2025 Apr 10:09727531251314999. doi: 10.1177/09727531251314999. Epub ahead of print. PMID: 40224300; PMCID: PMC11985480.
34. Jacob J, Krishnan VS, Sreeja S, Thampan RV. Differential Expression of Splicing Factor Gene by Estrogen Receptor Activation Factor. Mol Reprod Dev. 2025;92(4):e70023. doi:10.1002/mrd.70023
35. Geetu Rose Varghese, Vivek Vijay, Sreeja Sreedevi, Santhik S Lupitha, Priya Prabhakaran, Sushama Aswathyraj, Anitha P. Moorkoth, Niyas K Pulloor, Easwaran Sreekumar. Reproducible generation of Nipah virus pseudovirions with uniform expression of F and G surface glycoproteins for high-throughput neutralization assays. bioRxiv doi.org/10.1101/2025.04.07.647518
36. Akhil K Mohan, Lenkapothula Naresh Goud, G.S. Vinod Kumar. In Vitro and In Vivo Evaluation of PCL-PEG Nanomicelles for Paclitaxel Drug Release to Treat Breast Cancer ACS Applied Nano Materials May 23, 2025 DOI: 10.1021/acsanm.5c02333
37. Malik IS, Nair NK, B A, Mishra S, Unnithan S, Narayana C, Bhowmik D. Optimizing Branch Morphology in Gold Nanostars To Improve HER2-Targeted Cytotoxicity in HER2-Overexpressing Cancer Cells in the Presence of Serum Proteins. Langmuir . 2025 Jun 10. doi: 10.1021/acs.langmuir.5c00350. Epub ahead of print. PMID: 40494827.
38. Bhattacharyya C, Subramanian K, Uppili B, Biswas NK, Ramdas S, Tallapaka KB, Arvind P, Rupanagudi KV, Maitra A, Nagabandi T, De T, Singh K, Sharma P, Sharma N, Raghav SK, Prasad P, Soniya EV, Jaleel A, Nelson Sathi S, Joshi M, Joshi C, Lahiri M, Dixit S, Shashidhara LS, Senthil Kumar N, Lalhruaitluanga H, Nundanga L, Shivakumar V, Venkatasubramanian G, Rao NP, Ganie MA, Wani IA, Jha G, Dalal A, Bashyam MD, Varadwaj PK, Bs S, Simmhan Y, Jain C, Sundar D, Gupta I, Yadav P, Sinha H, Narayanan M, Raman K, Padinjat R, Sabarinathan R; GenomeIndia Consortium; Narahari Y, Ravindranath V, Thangaraj K, Sowpati DT, Faruq M, Basu A, Kahali B. Mapping genetic diversity with the GenomeIndia project.Nat Genet. 2025 Apr;57(4):767-773. doi: 10.1038/s41588-025-02153-x. Erratum in: Nat Genet. 2025 May 8. doi: 10.1038/s41588-025-02206-1. PMID: 40200122.
39. Muthuvel M, Ganapathy T, Spencer T, Raikar SS, Thangavel S, Srivastava A, Martin S. Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy. Front Immunol. 2025 May 9;16:1545549. doi: 10.3389/fimmu.2025.1545549. PMID: 40416968; PMCID: PMC12098533.
40. Maurya SK, Jaramillo-Gómez JA, Rehman AU, Gautam SK, Fatima M, Khan MA, Zaidi MAA, Khan P, Anwar L, Alsafwani ZW, Kanchan RK, Mohiuddin S, Pothuraju R, Vengoji R, Chirravuri Venkata R, Natarajan G, Bhatia R, Atri P, Perumal N, Chaudhary S, Lakshmanan I, Mahapatra S, Talmon GA, Cox JL, Smith LM, Santamaria-Barria JA, Ganti AK, Siddiqui JA, Cittelly DM, Batra SK, Nasser MW. Mucin 5AC Promotes Breast Cancer Brain Metastasis through cMET/CD44v6. Clin Cancer Res. 2025 Mar 3;31(5):921-935. doi: 10.1158/1078-0432.CCR-24-1977. PMID: 39760691; PMCID: PMC11882111.
41. John S, Kalathil D, Pothuraju R, Nair SA. Deciphering ETS2: An indispensable conduit to cancer. Biochim Biophys Acta Rev Cancer. 2025 Jun 7:189368. doi: 10.1016/j.bbcan.2025.189368. Epub ahead of print. PMID: 40490201.
42. Sivasailam A, Kumar KS, Jayaprasad AG, Jancy SV, Harikumar A, Unnikrishnan PS, Sivakumar KC, Tiffee PJJ, Halikar AM, Nithin SS, Pillai PR, Tiwari SK, Sanjeev VS, Surabhi AV, Santhoshkumar TR. Estrogen receptor alpha dynamics and plasticity during endocrine resistance. Biol Direct. 2025 Jun 13;20(1):70. doi: 10.1186/s13062-025-00653-8. PMID: 40514718.
43. Prakash A, Banerjee M. Neur-Ally: a deep learning model for regulatory variant prediction based on genomic and epigenomic features in brain and its validation in certain neurological disorders.NAR Genom Bioinform. 2025 Jun 13;7(2):lqaf080. doi: 10.1093/nargab/lqaf080. PMID: 40519652; PMCID: PMC12164584.
44. Ittycheria SS, Sivakumar KC, Patra D, Ramachandran B, Neetha RL, Warrier AV, Aiswariya MA, Kaviya S, Suman P, Narayanaswamy N, Srinivas P. Discovery of potential small molecule inhibitors against β-hCG: an in silico study with in vitro validation. RSC Adv. 2025 Jun 10;15(25):19561-19580. doi: 10.1039/d4ra08663e. PMID: 40503310; PMCID: PMC12150210.
45. Unnikrishnan K, Krishnankutty Chandrika S, Ram Kumar RM, Srinivas P. Tumor Suppressor miRNA-based Signatures in Triple Negative Breast Cancer: A Study Based on Big Data Analysis of Gene Expression Omnibus (GEO) Datasets and Its Validation. Asian Pac J Cancer Prev. 2025 Jun 1;26(6):2087-2095. doi: 10.31557/APJCP.2025.26.6.2087. PMID: 40542771.
46. Vrinda AM, Thangaraju M, Nair SA, Howarth GS, Pothuraju R. Unraveling the role of mucins and gut microbiota in gastrointestinal cancers chemoresistance. Biochim Biophys Acta Rev Cancer. Published online July 8, 2025. doi:10.1016/j.bbcan.2025.189385
47. Aman Munirpasha Halikar, Aneesh Chandrasekharan, Asha Lekshmi, Aswathy Sivasailam, Jain Tiffee P J, Shivanshu Kumar Tiwari, Aijaz Ahmad Rather and TR Santhoshkumar. Bax- Bcl-xL interaction dynamics during the progression of cell cycle and cell death using FLIM-FRET Cell Stress .Published 08.07.2025.
48. Akhila T.P, Darsana K.M, Rajesh Chandramohanadas. Functional Phenotyping of MMV Pandemic Response Box Identifies Stage and Mechanism-Specific Inhibitors against Blood Stage Plasmodium falciparum. ACS Infect Dis. 2025 Jul 11. doi: 10.1021/acsinfecdis.5c00319. Epub ahead of print. PMID: 40643161.
49. Das DJ, Jaikumar VS, Suryaletha K, Paul M, Shankar A, Nath SR, Thomas S. Probiotic Lacticaseibacillus paracasei from human gut microbiome against colistin-resistant Klebsiella pneumoniae: in vitro, in vivo and probiogenomic approaches. Benef Microbes. 2025 Apr 9:1-21. doi: 10.1163/18762891-bja00065. Epub ahead of print. PMID: 40312034.
50. Mallika AP, Sulajamani JP, Sivasankara MP, Menon RN, Banerjee M. Pro-inflammatory cytokine genetic variants show variable susceptibility to mild cognitive impairment, alzheimer's disease and frontotemporal dementia in South India. Neurogenetics. 2025 Jul 29;26(1):55. doi: 10.1007/s10048-025-00834-7. PMID: 40728724.

Book Chapter

1. Samlesh Kumari; Smrutirekha Mallick; Deepika S Channe; Narendra Kumar; Vandana Kumari; Ramesh Pothuraju. Significance of Millets in Gut Health. Traditional Foods Impact on Gut Health https://doi.org/10.1201/9781003514244
2. Deepthi Mohan; Manoj P; Ganesh Nair; Anish N P; Chandrabhas Narayana. Genetic analysis of Indigenous Tribal crops. Studies on Agriculture https://zentoks.com/journal-admin/uploads/articles/zentoks-sa-ch1.pdf
3. Deepa Narayanan; M. T. Giffin; P. V. Vinitha; Hima Sebastian; Midhun C. Dominic. Nanocoated Medical Devices: Prospects and Challenges. Nanoengineered Materials for Medical and Healthcare Applications doi.org/10.1002/9781119792192.ch14