PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair

Fathima Hameed J S, Anjali Devarajan , Devu Priya M S , Ahel Bhattacharyya , Mayur Balkrishna Shirude ,Debasree Dutta, Parimal Karmakar, and Ananda Mukherjee (2023)
BMC Cancer.

Nuclear PTEN localization contributes to DNA damage repair in endometrial adenocarcinoma and could have a diagnostic benefit for therapeutic management of the disease.

Mukherjee A *, Patterson AL*, George JW, Carpenter TJ, Madaj ZB, Hostetter G, Risinger JI, Teixeira JM (2018)
Mol Cancer Ther.     DOI: 10.1158/1535- 7163.MCT-17-1255. *authors contributed equally.

Enhanced expression of Histone chaperone APLF associate with breast cancer.

Majumder A, Syed KM, Mukherjee A, Babu M, Azeez JM, Sreeja S, Harikumar KB, Pillai MR, Dutta D. (2018)
Mol Cancer.     17:76. doi: 10.1186/s12943-018-0826-9.

Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.

Syed KM*, Joseph S*, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR. (2016)
J Cell Sci.     129:4576-4591. *authors contributed equally.

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair.

Vuono EA, Mukherjee A, Vierra DA, Adroved MM, Hodson C, Deans AJ, Howlett NG. (2016)
Sci Rep.     6:36439. doi: 10.1038/srep36439.

Phosphorylation of PTEN at STT motif is associated with DNA damage response.

Misra S, Mukherjee A, Karmakar P. (2014)
Mutat Res.     770:112-19.

Chapters in Book / Text

  • Debasree Dutta, Khaja Mohieddin Syed and Ananda Mukherjee (February 28th 2018). Histone Chaperones Regulate Mammalian Gene Expression, Gene Expression and Regulation in Mammalian Cells Fumiaki Uchiumi, IntechOpen, DOI: 10.5772/intechopen.71924.


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