Decoding the proteomic changes involved in the biofilm formation of Enterococcus faecalis SK460 to elucidate potential biofilm determinants.

Karthika. S, Lekshmi N, Joby John, Megha P. R, George S and Sabu Thomas (2019)
BMC Microbiology     19:146.DOI: 10.1186/s12866-0191527-2 2

Genome sequence of a multidrug-resistant Klebsiellapneumoniae ST78 with high colistin resistance isolated from a patient in India.

Merin Paul, Lekshmi Narendrakumar, Arya R. Vasanthakumary, Iype Joseph, Sabu Thomas (2019)
Journal of Global Antimicrobial Resistance     17, 187-188. https://doi.org/10.1016/j.jgar.2019.04.008

Molecular adaptations and antibiotic resistance in Vibrio cholerae: a communal challenge.

Lekshmi Narendrakumar,Sanjukta Sen Gupta, John B Johnson, Ramamurthy Thandavarayan and Sabu Thomas (2019)
Microbial Drug Resistance     http://doi.org/10.1089/mdr.2018.0354

Changing facades of Vibrio cholera: An enigma in the epidemiology of cholera

Lekshmi.N, Iype Joseph, T. Ramamurthy, Sabu Thomas (2018)
Indian Journal of Medical Research     147: 133-141.

Vibrio cholerae O1 gaining reduced susceptibility to doxycycline, India.

Lekshmi.N and Sabu Thomas (2018)
Journal of Global Antimicrobial Resistance,     12:141-142

Metataxonomic approach to decipher the polymicrobial burden in diabetic foot ulcer and its biofilm mode of infection.

Karthika S, Joby John, Megha P.R, George.S and Sabu Thomas (2018)
International Wound J.     15(3):473-481

Chapters in Book / Text

    1. Narendrakumar L., Das B., Paramasivan B., Rasu J., Thomas S, 2018. Quorum Quenching and Biofilm Inhibition: Alternative Imminent Strategies to Control the Disease Cholera. In: Kalia V.C (eds) Biotechnological Applications of Quorum Sensing Inhibitors. pp.63-85 Springer, Singapore https://doi.org/10.1007/978-981-10-9026-4_4.
    2. Das B., Paramasivan B., Rasu J., Narendrakumar L., Thomas S, 2018. Strategies Behind Biosensors for Food and Waterborne Pathogens. In: Kalia V.C (eds) Quorum Sensing and its Biotechnological Applications. pp.107-141 Springer, Singapore https://doi.org/10.1007/978-981-13-0848-2_8.
    3. Sudha A, Wilson P.A and Sabu Thomas, 2012. Psychrophiles - A plethora of perspectives. Bacterial Biochemistry and Biotechnology.Lambert Academic Publishing. pp. 158-167.
    4. S. PrincyAdline, Srinath N, SajalShrivastava and Sabu Thomas, 2010. Vibrio cholerae biofilm and virulence gene expression: A perception towards quorum sensing. In Cholera: Symptoms, Diagnosis and Treatment. (Eds.Evelyn L. Melbourne) Nova Science Publishers Inc. Hauppauge, NY, USA. pp. 123-133.
    5. S. PrincyAdline, R. Vinothkannan, RekhaArya and Sabu Thomas, 2010. Quorum Quenching: Imminent Targets in Vibrio cholerae. In Cholera: Symptoms, Diagnosis and Treatment. (Eds.Evelyn L. Melbourne) Nova Science Publishers Inc. Hauppauge, NY, USA. pp. 109-122.
    6. Sabu Thomas, S Jagadeeshan, P Kumar, SathishMundayoor and Yung Tse, 2010. Drinking Water Associated Pathology. Hand Book of Environmental and Waste Management, Volume 1 -Air and Water Pollution Control. (Eds. Yung-Tse Hung, Lawrence K. Wang, Nazih K. Shammas, USA).World Scientific Publishing Co. Pte.Ltd, Singapore.
    7. Jagadeeshan S, P. Kumar, WP Abraham and Sabu Thomas, 2009. The emerging multiple antibiotic resistance pattern in the environmental isolates of Vibrio cholerae isolated from S. Kerala.Antimicrobial Resistance: from Emerging Threat to Reality (Eds. Rubina Lawrence, Anil K Gulati, Gerrard Abraham). Narosa Publishing House Pvt. Ltd. New Delhi; pp. 241-245.
    8. Sabu Thomas, Praveen PP, Wilson P.A, Bibin T and Singh D.V, 2007. Molecular monitoring of Vibrio cholerae in the aquatic environments of Kerala.Environment & Human Health, Rajiv Gandhi Chair Pub.2 (Eds. Dr. P. Natarajan, Dr. C.S. Paulose, Dr. I.S. Bright Singh and Ms.PillaiRaji K), pp. 67-77.
    9. Sabu Thomas, Sandhya C Nair and R. Paul Murugan, 2002. A study on the water quality and microbiology profile of Sasthamkotta freshwater lake in Kollam district, Kerala.Ecology and Conservation of Lakes, Reservoirs and Rivers,(Ed. Dr.Arvind Kumar) pp.299-302.
    10. Sabu Thomas, 2002. Reservoirs of Kerala-Their unique potential and problems.Ecology and Conservation of Lakes, Reservoirs and Rivers,(Ed. Dr.Arvind Kumar) pp.620-629.
    11. Sabu Thomas, 2002. Benthic composition, Abundance and Zonal differentiation in the Peppara reservoir, S.Kerala, India,.Ecology and Conservation of Lakes, Reservoirs and Rivers,(Ed. Dr.Arvind Kumar) pp.630-635.

Submissions

  • Bacterial Whole Genome & Metagenome Sequence Submission

    1. Karthika S & Sabu Thomas. Draft genome sequencing of Enterococcus faecalis isolated from chronic diabetic ulcer Bioproject: PRJNA390699, Biosample: SAMN07249099, Acc.No. NIXL00000000
    2. Lekshmi N & Sabu Thomas. Vibrio cholerae strain W4-13, whole genome shotgun sequencing project, Bioproject: PRJNA390691, Biosample: SAMN07249013, Acc no.NIWX00000000
    3. Akhilandeswaree D & Sabu Thomas. Pseudomonas brenneri strain RGCB 108, whole genome shotgun sequencing project, Bioproject: PRJNA315753, Biosample: SAMN04569815 Acc no. LUXZ00000000 
    4. Akhilandeswaree D & Sabu Thomas. Pseudomonas simiae strain RGCB 73, whole genome shotgun sequencing project. Bioproject: PRJNA307220, Biosample:SAMN04517449Acc no. LVWZ00000000.
    5. Wilson P A & Sabu Thomas. Pseudomonas psychrophila strain RGCB 166, whole genome shotgun sequencing project. Bioproject:PRJNA278112, Biosample: SAMN03406680, Acc. No. LBHT00000000, Contigs Acc. No. LBHT01000001-LBHT01000150.
    6. Divya M.P and Sabu Thomas. Draft Genome Sequence of an Environmental Vibrio parahaemolyticus K23. Bioproject: PRJNA285022, Biosample: SAMN03735013, Acc.No. LQGU00000000
    7. Karthika S & Sabu Thomas.  Metagenome of Diabetic Ulcer. SRA Acc. no.: SRX1453631, Bioproject: PRJNA304366, Biosample: SAMN04299664

    PRIDE Archive Submission

    1. Comparitive Proteome analysis of Vibrio parahaemolyticus during planktonic and biofilm stages, Project Acc. no. PXD004354

    Genbank Submissions

    1. V. cholerae O1 biovar El Tor Haitian variant strains, cholera enterotoxin B-subunit (ctxB) gene, complete cds. Acc. nos. KU665401- KU665415 respectively.
    2. V. cholerae O1 biovar El Tor Haitian variant strains, toxin co-regulated pili A-subunit (tcpA) gene, complete cds. Acc. nos. KU725714-KU725733 respectively.
    3. V. cholerae non-O1/non-O139 strains ASH35-ASH42, 16S ribosomal RNA gene, partial sequence. Acc. nos. KX130907-KX130914 respectively.
    4. Pseudomonas psychrophila strain 166. 16S ribosomal RNA gene, partial sequence.Accession number. JX271040
    5. Cold shock protein from Psychrobacter sp. 331 isolated from Arctic sediment.Acc. no. JN024699
    6. Enterobacter spp. psychrophillic strains 16S rRNA gene sequence. Acc. nos. EU391589, FJ463411, FJ463410.
    7. Psychrotrophic bacteria from fjord water and sediments of Ny-Alesund area, Arctic.
      Acc. nos. KP204033-KP204050.
    8. A novel variant of tcpA gene from environmental strain of Vibrio cholerae, non-O1/non-O139.Acc. no. EU362122.
    9. Vibrio cholerae non-O1/nonO139 strain AMVC 16S ribosomal RNA gene, partial sequence. Acc. no JX987303.1
    10. Vibrio cholerae O1 biovar El Tor strains VCW4, C1, C3, C5 cholera enterotoxin B-subunit (ctxB) gene, complete cds. Acc. nos. KF042305-KF042308 respectively.
    11. Vibrio cholerae O1 biovar El Tor strains VCW4, C1, C3, C5 DNA topoisomerase IV subunit A (parC) gene, partial cds. Acc. nos. KF741367-KF741370 respectively.
    12. Wohlfahrtiimonaschitiniclastica strain SK202 16S ribosomal RNA   gene partial sequence. Acc. no KM030600.
    13. Bacillus thuringiensis strain S19, Bacillus stratosphericusstrain S6, Bacilluslicheniformis strain S9, Bacillus sp. S16 16S ribosomal RNA gene, partial sequence. Acc.nos.KF052984 KF052987respectively.
    14. Streptomyces sp. A742 16S ribosomal RNA gene, partial sequence. Acc. no. KC153537.

Absracts / Presentations / Invited Lectures

Contact

Rajiv Gandhi Centre for Biotechnology (RGCB),
Thycaud Post, Poojappura,
Thiruvananthapuram - 695 014, Kerala, India
+91-471-2529400 | 2347975 | 2348753
+91-471-2348096
webmaster@rgcb.res.in