Genetic and virulence characterisation of Vibrio parahaemolyticus isolated from Indian coast

Divya M.P, Ramamurthy T, Sabu Thomas( 2020).
BMC Microbiology     20, 62. https://doi.org/10.1186/s12866-020-01746-2

Deciphering the Cold Adaptive Mechanisms in Pseudomonas psychrophila MTCC12324 Isolated from the Arctic at 79° N.

Wilson, P.A, Raghunandanan, S, Gopinath, V. Karthika S, Sabu Thomas (2020)
Current Microbiol.     https://doi.org/10.1007/s00284-020-02006-2

Bacteriological profile of multidrug resistant Gram negative bacilli causing urinary tract infection in paediatric age group in a tertiary care centre.

Lijitha S.G, Resmi Rajan, Karthika S, Sabu Thomas(2020).
Journal of Medical Science and Clinical Research     08 (03):498-504. https://dx.doi.org/10.18535/jmscr/v8i3.87

Decoding the proteomic changes involved in the biofilm formation of Enterococcus faecalis SK460 to elucidate potential biofilm determinants.

Karthika. S, Lekshmi N, Joby John, Megha P. R, Sanil George and Sabu Thomas(2019).
BMC Microbiology     19:146.DOI: 10.1186/s12866-019-1527-2

Molecular adaptations and antibiotic resistance in Vibrio cholerae: a communal challenge.

Lekshmi.N, Gupta S.S, Johnson J.B, T. Ramamurthy and Sabu Thomas(2019)
Microbial Drug Resistance     DOI:10.1089/mdr.2018.0354

Genome sequence of a multidrug-resistant Klebsiella pneumoniae ST78 with high colistin resistance isolated from a patient in India.

Merin.P, Lekshmi.N, Vasanthakumary A. R, Iype Joseph,Sabu Thomas.(2019)
Journal of Global Antimicrobial Resistance     17: 187-188. DOI:10.1016/j.jgar.2019.04.008

Chapters in Book / Text

    1. Merin Paul, Vidhyalakshmi M, Lekshmi N, Iype Joseph, Sabu Thomas.2020. Status Quo of Omics Technologies in Analyzing the Genetic Mediators of Anti-Microbial Resistance at Sub-MIC Concentrations. Sabu Thomas et al (eds.) Antimicrobial Resistance: Global Challenges and Future Interventions. Springer Nature Singapore Pte Ltd. (In press)
    2. Karthika S, Lekshmi N, Akhilandeswarre D, Devika Das J, Aparna Shankar, Iype Joseph, Sabu Thomas. 2020. Evolving state-of-the-art technologies in Biofilm research: from static to real-time models. Sabu Thomas et al.(eds)'Emerging Concepts in Bacterial Biofilms: Molecular Mechanisms and Control Strategies. pp 319-369. Cambridge Scholars Publisher, UK
    3. Narendrakumar L., Das B., Paramasivan B., Rasu J., Thomas S, 2018. Quorum Quenching and Biofilm Inhibition: Alternative Imminent Strategies to Control the Disease Cholera. In: Kalia V.C (eds) Biotechnological Applications of Quorum Sensing Inhibitors. pp.63-85 Springer, Singapore https://doi.org/10.1007/978-981-10-9026-4_4.
    4. Das B., Paramasivan B., Rasu J., Narendrakumar L., Thomas S, 2018. Strategies Behind Biosensors for Food and Waterborne Pathogens. In: Kalia V.C (eds) Quorum Sensing and its Biotechnological Applications. pp.107-141 Springer, Singapore https://doi.org/10.1007/978-981-13-0848-2_8.
    5. Sudha A, Wilson P.A and Sabu Thomas, 2012. Psychrophiles - A plethora of perspectives. Bacterial Biochemistry and Biotechnology.Lambert Academic Publishing. pp. 158-167.
    6. S. PrincyAdline, Srinath N, SajalShrivastava and Sabu Thomas, 2010. Vibrio cholerae biofilm and virulence gene expression: A perception towards quorum sensing. In Cholera: Symptoms, Diagnosis and Treatment. (Eds.Evelyn L. Melbourne) Nova Science Publishers Inc. Hauppauge, NY, USA. pp. 123-133.
    7. S. PrincyAdline, R. Vinothkannan, RekhaArya and Sabu Thomas, 2010. Quorum Quenching: Imminent Targets in Vibrio cholerae. In Cholera: Symptoms, Diagnosis and Treatment. (Eds.Evelyn L. Melbourne) Nova Science Publishers Inc. Hauppauge, NY, USA. pp. 109-122.
    8. Sabu Thomas, S Jagadeeshan, P Kumar, SathishMundayoor and Yung Tse, 2010. Drinking Water Associated Pathology. Hand Book of Environmental and Waste Management, Volume 1 -Air and Water Pollution Control. (Eds. Yung-Tse Hung, Lawrence K. Wang, Nazih K. Shammas, USA).World Scientific Publishing Co. Pte.Ltd, Singapore.
    9. Jagadeeshan S, P. Kumar, WP Abraham and Sabu Thomas, 2009. The emerging multiple antibiotic resistance pattern in the environmental isolates of Vibrio cholerae isolated from S. Kerala.Antimicrobial Resistance: from Emerging Threat to Reality (Eds. Rubina Lawrence, Anil K Gulati, Gerrard Abraham). Narosa Publishing House Pvt. Ltd. New Delhi; pp. 241-245.
    10. Sabu Thomas, Praveen PP, Wilson P.A, Bibin T and Singh D.V, 2007. Molecular monitoring of Vibrio cholerae in the aquatic environments of Kerala.Environment & Human Health, Rajiv Gandhi Chair Pub.2 (Eds. Dr. P. Natarajan, Dr. C.S. Paulose, Dr. I.S. Bright Singh and Ms.PillaiRaji K), pp. 67-77.
    11. Sabu Thomas, Sandhya C Nair and R. Paul Murugan, 2002. A study on the water quality and microbiology profile of Sasthamkotta freshwater lake in Kollam district, Kerala.Ecology and Conservation of Lakes, Reservoirs and Rivers,(Ed. Dr.Arvind Kumar) pp.299-302.
    12. Sabu Thomas, 2002. Reservoirs of Kerala-Their unique potential and problems.Ecology and Conservation of Lakes, Reservoirs and Rivers,(Ed. Dr.Arvind Kumar) pp.620-629.
    13. Sabu Thomas, 2002. Benthic composition, Abundance and Zonal differentiation in the Peppara reservoir, S.Kerala, India,.Ecology and Conservation of Lakes, Reservoirs and Rivers,(Ed. Dr.Arvind Kumar) pp.630-635.

Submissions

  • Bacterial Whole Genome & Metagenome Sequence Submission

    1. Karthika S & Sabu Thomas. Draft genome sequencing of Enterococcus faecalis isolated from chronic diabetic ulcer Bioproject: PRJNA390699, Biosample: SAMN07249099, Acc.No. NIXL00000000
    2. Lekshmi N & Sabu Thomas. Vibrio cholerae strain W4-13, whole genome shotgun sequencing project, Bioproject: PRJNA390691, Biosample: SAMN07249013, Acc no.NIWX00000000
    3. Akhilandeswaree D & Sabu Thomas. Pseudomonas brenneri strain RGCB 108, whole genome shotgun sequencing project, Bioproject: PRJNA315753, Biosample: SAMN04569815 Acc no. LUXZ00000000 
    4. Akhilandeswaree D & Sabu Thomas. Pseudomonas simiae strain RGCB 73, whole genome shotgun sequencing project. Bioproject: PRJNA307220, Biosample:SAMN04517449Acc no. LVWZ00000000.
    5. Wilson P A & Sabu Thomas. Pseudomonas psychrophila strain RGCB 166, whole genome shotgun sequencing project. Bioproject:PRJNA278112, Biosample: SAMN03406680, Acc. No. LBHT00000000, Contigs Acc. No. LBHT01000001-LBHT01000150.
    6. Divya M.P and Sabu Thomas. Draft Genome Sequence of an Environmental Vibrio parahaemolyticus K23. Bioproject: PRJNA285022, Biosample: SAMN03735013, Acc.No. LQGU00000000
    7. Karthika S & Sabu Thomas.  Metagenome of Diabetic Ulcer. SRA Acc. no.: SRX1453631, Bioproject: PRJNA304366, Biosample: SAMN04299664

    PRIDE Archive Submission

    1. Comparitive Proteome analysis of Vibrio parahaemolyticus during planktonic and biofilm stages, Project Acc. no. PXD004354

    Genbank Submissions

    1. V. cholerae O1 biovar El Tor Haitian variant strains, cholera enterotoxin B-subunit (ctxB) gene, complete cds. Acc. nos. KU665401- KU665415 respectively.
    2. V. cholerae O1 biovar El Tor Haitian variant strains, toxin co-regulated pili A-subunit (tcpA) gene, complete cds. Acc. nos. KU725714-KU725733 respectively.
    3. V. cholerae non-O1/non-O139 strains ASH35-ASH42, 16S ribosomal RNA gene, partial sequence. Acc. nos. KX130907-KX130914 respectively.
    4. Pseudomonas psychrophila strain 166. 16S ribosomal RNA gene, partial sequence.Accession number. JX271040
    5. Cold shock protein from Psychrobacter sp. 331 isolated from Arctic sediment.Acc. no. JN024699
    6. Enterobacter spp. psychrophillic strains 16S rRNA gene sequence. Acc. nos. EU391589, FJ463411, FJ463410.
    7. Psychrotrophic bacteria from fjord water and sediments of Ny-Alesund area, Arctic.
      Acc. nos. KP204033-KP204050.
    8. A novel variant of tcpA gene from environmental strain of Vibrio cholerae, non-O1/non-O139.Acc. no. EU362122.
    9. Vibrio cholerae non-O1/nonO139 strain AMVC 16S ribosomal RNA gene, partial sequence. Acc. no JX987303.1
    10. Vibrio cholerae O1 biovar El Tor strains VCW4, C1, C3, C5 cholera enterotoxin B-subunit (ctxB) gene, complete cds. Acc. nos. KF042305-KF042308 respectively.
    11. Vibrio cholerae O1 biovar El Tor strains VCW4, C1, C3, C5 DNA topoisomerase IV subunit A (parC) gene, partial cds. Acc. nos. KF741367-KF741370 respectively.
    12. Wohlfahrtiimonaschitiniclastica strain SK202 16S ribosomal RNA   gene partial sequence. Acc. no KM030600.
    13. Bacillus thuringiensis strain S19, Bacillus stratosphericusstrain S6, Bacilluslicheniformis strain S9, Bacillus sp. S16 16S ribosomal RNA gene, partial sequence. Acc.nos.KF052984 KF052987respectively.
    14. Streptomyces sp. A742 16S ribosomal RNA gene, partial sequence. Acc. no. KC153537.

Absracts / Presentations / Invited Lectures

Contact

Rajiv Gandhi Centre for Biotechnology (RGCB),
Thycaud Post, Poojappura,
Thiruvananthapuram - 695 014, Kerala, India
+91-471-2529400 | 2347975 | 2348753
+91-471-2348096
webmaster@rgcb.res.in

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