Rajiv Gandhi Centre for Biotechnology (RGCB) has its main campus at Jagathy in Thiruvananthapuram. The campus concentrates on Disease Biology Research and does innovative research in cellular and molecular mechanisms of human, animal and plant diseases. The program is designed to make the institute a world-class research establishment in molecular and medical aspects of human, animal and plant disease biology integrating theory, modeling, simulation and experiential science encompassing disciplines such as biology, genetics, chemical biology, immunology and many other disciplines. Our mission is to understand the underlying biology of human, animal and plant diseases and eventually develop a new complimentary approach to train individuals in translational biology and promote collaborations between clinical, veterinary and agricultural professionals with basic biology scientists. This we hope will serve as a catalyst to move discoveries effectively to implementation for public benefit.

The range of disease areas, which are actively studied, includes cancer, atherosclerosis & heart disease, tuberculosis, viral infections, cholera, neurological disorders and reproductive problems as well fungal diseases in spices. In addition, application of modern technologies such as high throughput sequencing, DNA bar-coding, synthetic biology, nano-biotechnology and chemical biology are used to develop delivery systems, understand the fundamentals of cellular function during disease and also characterize the molecular taxonomy of disease manifestations.