Rajiv Gandhi Centre for Biotechnology (RGCB), Department of Biotechnology, Government of India

Fabrication of cytotoxic mirror image nanopores

Neilah Firzan Ca, Kalyanashis Jana, Sreelakshmi Radhakrishnan, Rifat Aara, Mubeena S, Radhika Nair, Harsha Bajaj, Ulrich Kleinekathöfer, Kozhinjampara R Mahendran

Nature Communications doi: 10.1038/s41467-025-64025-6

A Dynamic Sugar-Selective Bacterial Nanopore for Targeted Antibiotic Transport

Sharavanakkumar SK, Bibhab Bandhu Majumdar, Devika Vikraman, Kajori Mahanta, Aparna Soman, Arumugam Rajavelu, Jagannath Mondal, Kozhinjampara R. Mahendran (2025)

Small doi.org/10.1002/smll.202502110

Functionally Active Synthetic α-Helical Pores

Smrithi Krishnan R, Neilah Firzan CA, and Kozhinjampara R. Mahendran (2024)

Accounts of Chemical Research https://doi.org/10.1021/acs.accounts.4c00101

Conformational flexibility driving charge-selective substrate translocation across a bacterial transporter

Devika Vikraman, Bibhab Bandhu Majumdar, Sharavanakkumar SK, Conrad Weichbrodt, Niels Fertig, Mathias Winterhalter, Jagannath Mondal and Kozhinjampara R. Mahendran (2024)

Chemical Science https://doi.org/10.1039/D4SC00345D

Sensing PEGylated Peptide Conformations Using a Protein Nanopore

Remya Satheesan, Devika Vikraman, Parvathy Jayan, Vinesh Vijayan, Catalin Chimerel, and Kozhinjampara R. Mahendran (2023)

Nano Letters doi.org/10.1021/acs.nanolett.3c03247

Synthetic α-Helical Nanopore Reactor for Chemical Sensing

Anjali Devi Das, Vidhu K, Smitha Devi S, and Kozhinjampara R Mahendran (2023)

JACS Au doi.org/10.1021/jacsau.3c00221

Electrostatic Filtering of Polypeptides Through Membrane Protein Pores

Devika Vikraman, Smrithi Krishnan R, Remya Satheesan, Anjali Devi Das, Kozhinjampara R Mahendran (2022)

Chemistry: An Asian Journal doi.org/10.1002/asia.202200891

Assembly of transmembrane pores from mirror-image peptides

Smrithi Krishnan R, Kalyanashis Jana, Amina H. Shaji, Karthika S. Nair, Anjali Devi Das, Devika Vikraman, Harsha Bajaj, Ulrich Kleinekathöfer & Kozhinjampara R. Mahendran (2022)

Nature Communications doi.org/10.1038/s41467-022-33155-6

Selective Translocation of Cyclic Sugars through Dynamic Bacterial Transporter.

Devika Vikraman, Remya Satheesan, Mangaiyarkarasi Rajendran, Nisha Asok Kumar, John Bernet Johnson, Smrithi Krishnan R, and Kozhinjampara R. Mahendran (2022)

ACS Sensors doi.org/10.1021/acssensors.2c00943

Assembly of alpha-helical transmembrane pores through an intermediate state

Neethu Puthumadathil, Smrithi Krishnan R, Greeshma S Nair, Kozhinjampara R Mahendran(2022)

Nanoscale doi.org/10.1039/D2NR00556E

Designed alpha-helical barrels for charge-selective peptide translocation.

Krishnan R S, Puthumadathil N, Shaji A, Kumar KS, Mohan G, Mahendran KR^* (2020)

Chemical Science https://doi.org/10.1039/D0SC04856A

Nanopore Passport Control for Substrate Specific Translocation.

Vikraman D, Satheesan R, Kumar KS, Mahendran KR^* (2020)
*Corresponding author

ACS Nano doi: 10.1021/acsnano.9b09408.

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Mahendran K .R, PhD

Scientist E-II

Selected Publications