Selected Publications

Mechanism of calcium potentiation in alpha7 nicotinic acetylcholine receptor.

Kathiresan Natarajan^*, Nuriya Mukhtasimova^* , Jeremías Corradi , Matías Lasala , Cecilia Bouzat, Steven M. Sine (2020)

Journal of General Physiology 152, e202012606 (2020) DOI: https://doi.org/10.1085/jgp.202012606
Spotlighted in Research News (^*equal contribution)

Molecular interactions between tubulin tails and glutamylases reveal determinants of glutamylation patterns.

Kathiresan Natarajan^*, Sudarshan Gadadhar, Judith Souphron, Maria M Magiera, Carsten Janke^* (2017)

EMBO Reports 18,1013-1026, (2017) DOI: https://doi.org/10.15252/embr.201643751
^*Corresponding author

Mutation of the α-tubulin Tuba1a leads to straighter microtubules and perturbs neuronal migration.

Richard Belvindrah, Kathiresan Natarajan, Preety Shabajee, Elodie Bruel-Jungerman, Jennifer Bernard, Marie Goutierre, Imane Moutkine, Xavier H Jaglin, Mythili Savariradjane, Theano Irinopoulou, Jean-Christophe Poncer, Carsten Janke, Fiona Francis (2017)

Journal of Cell Biology 216, 2443-2461,(2017) DOI: https://doi.org/10.1083/jcb.201607074
Spotlighted in Commentary

Relating nucleotide dependent conformational changes in free tubulin dimers to tubulin assembly.

Kathiresan Natarajan, Jagan Mohan, Sanjib Senapati (2013)

Biopolymers 99, 282-291, (2013) DOI: https://doi.org/10.1002/bip.22153
Spotlighted on Journal Cover

Understanding the Basis of Drug Resistance of the Mutants of ??-Tubulin Dimer via Molecular Dynamics Simulations.

Kathiresan Natarajan, Sanjib Senapati (2012)

PloS one 7, e4235, (2012) DOI: https://doi.org/10.1371/journal.pone.0042351

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Abstracts / Presentations / Invited Lectures

Scientific Presentations

“Covid19 vaccine research, development and prospects” Madurai Kamaraj University, Tamil Nadu, India. 6 August, 2021
“Recent progress on neutralising antibodies and small molecules drug discovery against SARS-CoV-2” Sree Sankara College, Kalady, Kottayam, Kerala, India. 7 September 2020.
“Mechanism of calcium potentiation in α7 nicotinic acetylcholine receptor.” Young Researchers in Life Science Congress, 16-18 June 2021.
“Mapping the structural and nucleotide-regulated dynamics of Tubulin.” Charge Transfer Modeling in Chemistry: New methods and solutions for a long-standing problem. Chime ParisTech, Paris, France. 07-10 April 2015.
“Probing the conformational flexibility of Tubulin in GTP bound, GDP bound and nucleotide-free states” CECAM workshop on Protein assemblies at the interface of functionalized materials. EPFL, Lausanne, Switzerland, 17-19 September 2014.
“Molecular dynamics simulations of FtsZ and Tubulin: Effects of nucleotide states and mutations” Institut Curie, France. 03 October 2013.
“Understanding the basis of drug resistance of the mutants of αβ-Tubulin dimer via molecular dynamics simulations” Tata Institute of Fundamental Research (TIFR), India. 27 February 2013.
“Relating Nucleotide-dependent conformational changes in free tubulin dimers to tubulin assembly” in RSC west India section Ph.D. student’s symposium. Goa University, India. 3-4 September 2010.

Kathiresan Natarajan, PhD

Scientist C