Understanding the influence of antipsychotic drugs on global methylation events and its relevance in treatment response.

B Swathy, Saradalekshmi KR, Nair IV, Nair C, Moinak Banerjee. (2017)
Epigenomics     2017, Accepted

Haloperidol induces pharmacoepigenetic response by modulating miRNA expression, global DNA methylation and expression profiles of methylation maintenance genes and genes involved in neurotransmission in neuronal cells.

B Swathy, Saradalekshmi KR, Nair IV, Nair C, Moinak Banerjee. (2017)
PLoS ONE     12(9): e0184209

Pharmacoepigenomic response of antipsychotic drugs on pharmacogenes is mediated by microRNAs.

B Swathy, KR Saradalekshmi, Indu V Nair, Chandrasekharan Nair and Moinak Banerjee (2017)
Epigenomics     9(6):811-821,2017

Understanding epigenetics of Schizophrenia in the backdrop of its antipsychotic drug therapy.

B Swathy, Moinak Banerjee . (2017)
Epigenomics     9, 5, 721-736, 2017

Serotonin Transporters in Theranostics of neuropsychiatric disorders. Ed. Gokare A. Ravishankar, Akula Ramakrishna, Serotonin and Melatonin: Their Functional Role in Plants, Food, Phytomedicine, and Human Health.

Swathy B, Moinak Banerjee. (2016)
Taylor and Francis CRC Press     Chapter 35, 539-550 2016

Submissions

  • Gene Bank

    1. AY310165 Homo sapiens truncated proliferating cell nuclear antigen (PCNA) gene, complete cds.
    2. AY310164 Homo sapiens PCNA gene, exon 1 and partial cds.
    3. AY310163 Homo sapiens PCNA gene, exon 1 and partial cds.
    4. AY310162 Homo sapiens PCNA gene, exon 1 and partial cds.
    5. Y490254 Homo sapiens P-glycoprotein (MDR1) gene, partial cds.
    6. NM_000015 Homo sapiens N-acetyltransferase 2 (arylamine N-acetyltransferase)
    7. AY847950 Cytochrome b gene, partial sequence; mitochondrial of H. puera
    8. AY847951 NADH dehydrogenase subunit-4(ND4) gene, partial sequence; mitochondrial of H. puera C.
    9. AY847952 Cytochrome b gene, partial sequence; mitochondrial of H. puera C. (Coimbatore)
    10. AY847953 Cytochrome oxidase subunit I (COI) gene, partial sequence; mitochondrial of H. puera C.
    11. AY847954 NADH dehydrogenase subunit 1 (ND1) gene, partial sequence; mitochondrial of H. puera C.
    12. AY571148 Cytochrome oxidase I subunit of H. puera C.
    13. AY572232 16S rRNA gene of H. puera C.
    14. AY572235 Cytochrome oxidase gene of H. puera C.
    15. AY575214 12SrRNA gene of H. puera C.
    16. AY572233 28S ribosomal RNA gene of H. puera C.
    17. AY572234 Beta-tubulin intron gene of H. puera C.
    18. AY572236 18s ribosomal RNA gene of H. puera C.
    19. AY572237 Elongation factor I alpha introns of H. puera C.
    20. AY572238 Wingless gene of H. puera C.
    21. AY575215 Elongation factor I alpha gene of H. puera C.
    22. AY847957 Tabanus atratus calo protein-like mRNA, partial cds
    23. AY847955 Moricin I mRNA, partial cds of H. puera C.
    24. AY847956 Moricin II mRNA, partial cds of H. puera C.

Software

    1. Developed Allele Typer a Windows based Allele typing software used for mutation studies.
    2. Developed Genome Profile Analysis (GPA) a windows based software used for mutation analysis on genes of Pharmacogenomic and Immunogenetic interests.
    3. Developed GENOPACK a Linux based software for Allele sequence matching, Sequence Alignment, Complementary and reverse complementary strand generation, Protein translation, Position Matching, Motif matching, Restriction Mapping, Consensus sequence generation, Searching for open reading frames and the corresponding patterns and supports Format conversion.
    4. Developed software, Psychiatric Patient Management System (PPMS) is a PHP PERL based patient data management software based on DSM IV criteria. All the commonly used psychiatric rating scales and side effects rating scales are integrated into the software. It automatically scores the patients positive, negative, cognitive and overall symptoms profile at initial presentation and subsequent followups. It is useful to clinicians, researchers, public health professionals and health inspectors.

Absracts / Presentations / Invited Lectures

Contact

Rajiv Gandhi Centre for Biotechnology (RGCB),
Thycaud Post, Poojappura,
Thiruvananthapuram - 695 014, Kerala, India
+91-471-2529400 | 2347975 | 2348753
+91-471-2348096
webmaster@rgcb.res.in