Publications List

  1. Sharaf SS, Lekshmi A, S A, K G A, Jyothi S P A, Chandrasekharan A, Somanathan T, Santhosh Kumar TR, K S. A multiplex immunoprofiling approach for detecting the co-localization of breast cancer biomarkers using a combination of Alexafluor - Quantum dot conjugates and a panel of chromogenic dyes. Pathol Res Pract. 2024 Jan;253:155033. doi: 10.1016/j.prp.2023.155033. Epub 2023 Dec 12. PMID: 38134837.
  2. Rajan D, Amrutha M, George S, Susmitha A, Anburaj AA, Nampoothiri KM. Molecular cloning, overexpression, characterization, and In silico modelling analysis of a novel GDSL autotransporter-dependent outer membrane lipase (OML) of Pseudomonas guariconensis. Int J Biol Macromol. 2024 Jan;255:128050. doi: 10.1016/j.ijbiomac.2023.128050. Epub 2023 Nov 20. PMID: 37992946.
  3. Chandrasekharan A, Tiwari SK, Munirpasha HA, Sivasailam A, Jayaprasad AG, Harikumar A, Santhoshkumar TR. Genetically encoded caspase sensor and RFP-LC3 for temporal analysis of apoptosis-autophagy. Int J Biol Macromol. 2024 Feb;257(Pt 2):128807. doi: 10.1016/j.ijbiomac.2023.128807. Epub 2023 Dec 14. PMID: 38101685.
  4. Augustine L, Varghese L, Kappachery S, Ramaswami VM, Surendrababu SP, Sakuntala M, Thomas G. Comparative analyses reveal a phenylalanine ammonia lyase dependent and salicylic acid mediated host resistance in Zingiber zerumbet against the necrotrophic soft rot pathogen Pythium myriotylum. Plant Sci. 2024 Jan 3;340:111972. doi: 10.1016/j.plantsci.2023.111972. Epub ahead of print. PMID: 38176527.
  5. Jose M, Fasaludeen A, Pavuluri H, Rudrabhatla PK, Chandrasekharan SV, Jose J, Banerjee M, Sundaram S, Radhakrishnan A, Menon RN. Metabolic causes of pediatric developmental & epileptic encephalopathies (DEE)- genetic variant analysis in a south Indian cohort. Seizure. 2024 Jan 3;115:20-27. doi: 10.1016/j.seizure.2023.12.017. Epub ahead of print. PMID: 38183824.
  6. Barkeer S, Pothuraju R, Malakar P, Pimentel TC, Siddiqui JA, Nair SA. Gum acacia dietary fiber: Significance in immunomodulation, inflammatory diseases, and cancer. Phytother Res. 2024 Jan 25. doi: 10.1002/ptr.8125. Epub ahead of print. PMID: 38272848.
  7. Shaji F, Mohanan NK, Shahzad S, V P G, Bangalore Prabhashankar A, Sundaresan NR, Laishram RS. Proto-oncogene cSrc-mediated RBM10 phosphorylation arbitrates anti-hypertrophy gene program in the heart and controls cardiac hypertrophy. Life Sci. 2024 Feb 1;341:122482. doi: 10.1016/j.lfs.2024.122482. Epub ahead of print. PMID: 38309577.
  8. Satheesan R, Vikraman D, Jayan P, Vijayan V, Chimerel C, Mahendran KR. Sensing PEGylated Peptide Conformations Using a Protein Nanopore. Nano Lett. 2024 Feb 5. doi: 10.1021/acs.nanolett.3c03247. Epub ahead of print. PMID: 38316144.
  9. Nikhil Bharambe, Ketul Saharan, Dileep Vasudevan, Sandip Basak. Cryo-EM structure of a 55-kDa nucleoplasmin protein. Biophysical Journal doi.org/10.1016/j.bpj.2023.11.1194
  10. Mohanan NK, Shaji F, Sudheesh AP, Arathi BP, Sundaresan NR, Laishram RS. Star-PAP controls oncogene expression through primary miRNA 3'-end formation to regulate cellular proliferation and tumour formation. Biochim Biophys Acta Mol Basis Dis. 2024 Feb 14:167080. doi: 10.1016/j.bbadis.2024.167080. Epub ahead of print. PMID: 38364942.
  11. Kalishwaralal K, Azeez Nazeer A, Induja DK, Keerthana CK, Shifana SC, Anto RJ. Enhanced extracellular vesicles mediated uttroside B (Utt-B) delivery to Hepatocellular carcinoma cell: Pharmacokinetics based on PBPK modelling. Biochem Biophys Res Commun. 2024 Feb 11;703:149648. doi: 10.1016/j.bbrc.2024.149648. Epub ahead of print. PMID: 38368675.
  12. Jabeena CA, Rajavelu A. Histone globular domain epigenetic modifications: The regulators of chromatin dynamics in malaria parasite. Chembiochem. 2024 Feb 16;25(4):e202300596. doi: 10.1002/cbic.202300596. Epub 2024 Jan 19. PMID: 38078518.
  13. Pothuraju R, Khan I, Jain M, Bouvet M, Malafa M, Roy HK, Kumar S, Batra SK. Colorectal cancer murine models: Initiation to metastasis. Cancer Lett. 2024 Feb 13:216704. doi: 10.1016/j.canlet.2024.216704. Epub ahead of print. PMID: 38360138.
  14. Jayaprasad AG, Chandrasekharan A, Arun Jyothi SP, John Sam SM, Santhoshkumar TR, Pillai MR. Telomerase inhibitors induce mitochondrial oxidation and DNA damage-dependent cell death rescued by Bcl-2/Bcl-xL. Int J Biol Macromol. 2024 Feb 23:130151. doi: 10.1016/j.ijbiomac.2024.130151. Epub ahead of print. PMID: 38403227.
  15. Jayalekshmi VS, Jagannath RS, Sreelekshmi S, Rafeekha P, Vidyalekshmy R, Ramachandran S. Maternal hypercholesterolemia during gestation is associated with elevated lipid levels of two-day-old neonates. Mol Cell Biochem. 2024 Feb;479(2):363-371. doi: 10.1007/s11010-023-04739-7. Epub 2023 Apr 19. PMID: 37074503.
  16. Saharan K, Baral S, Shaikh NH, Vasudevan D. Structure-function analyses reveal Arabidopsis thaliana HDA7 to be an inactive histone deacetylase. Curr Res Struct Biol. 2024 Feb 23;7:100136. doi: 10.1016/j.crstbi.2024.100136. PMID: 38463934; PMCID: PMC10920125.
  17. Thazhackavayal Baby B, Kulkarni AM, Gayam PKR, Harikumar KB, Mathew Aranjani J. Beyond cyclopamine: Targeting Hedgehog signaling for cancer intervention. Arch Biochem Biophys. 2024 Mar 1:109952. doi: 10.1016/j.abb.2024.109952. Epub ahead of print. PMID: 38432565.
  18. Indu PS, Anish TS, Chintha S, Libu GK, Tony L, Siju NS, Sreekumar E, Santhoshkumar A, Aravind R, Saradadevi KL, Sunija S, Johnson J, Anupriya MG, Mathew T, Reena KJ, Meenakshy V, Namitha P, Kumar NP, Kumari R, Mohamed AJ, Nagpal B, Sarkar S, Sadanandan R, Velayudhan R. The burden of dengue and force of infection among children in Kerala, India; seroprevalence estimates from Government of Kerala-WHO Dengue study. Lancet Reg Health Southeast Asia. 2023 Dec 11;22:100337. doi: 10.1016/j.lansea.2023.100337. PMID: 38482148; PMCID: PMC10934323.
  19. Binithamol K. Polakkattil, Neetha N. Vellichirammal, Indu V. Nair, Chandrasekharan M. Nair and Moinak Banerjee. Methylome-wide and meQTL analysis helps to distinguish treatment response from non-response and pathogenesis markers in schizophrenia. Frontiers in Psychiatry, 15, 2024
  20. Roshny Prasad, Anil Kadam, Vinitha Vinod Padippurackal, Aparna Pulikuttymadom Balasubramanian, Naveen Kumar Chandrakumaran, Kartik Suresh Rangari, Pawan Dnyaneshwar Khangar, Harikrishnan Ajith, Kathiresan Natarajan, Rajesh Chandramohanadas & Shijulal Nelson-Sathi (2024) Discovery of small molecule entry inhibitors targeting the linoleic acid binding pocket of SARS-CoV-2 spike protein, Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2024.2327537
  21. Harikumar KB, Vijayan Y, Sandhu JS. Modulatory Role of Phytochemicals/Natural Products in Cancer Immunotherapy. Curr Med Chem. 2024 Feb 15. doi: 10.2174/0109298673274796240116105555. Epub ahead of print. PMID: 38549529.
  22. Choudhury D, Ghosh D, Mondal M, Singha D, Pothuraju R, Malakar P. Polyploidy and mTOR signaling: a possible molecular link. Cell Commun Signal. 2024 Mar 27;22(1):196. doi: 10.1186/s12964-024-01526-9. PMID: 38539200; PMCID: PMC10976710.
  23. Vijayakumar S, Sakuntala M. Validation of reference gene stability for normalization of RT-qPCR in Phytophthora capsici Leonian during its interaction with Piper nigrum L. Sci Rep. 2024 Mar 27;14(1):7331. doi: 10.1038/s41598-024-58139-y. PMID: 38538851; PMCID: PMC10973370.
  24. Indu S, Devi AN, Sahadevan M, Sengottaiyan J, Basu A, K SR, Kumar PG. Expression profiling of stemness markers in testicular germline stem cells from neonatal and adult Swiss albino mice during their transdifferentiation in vitro. Stem Cell Res Ther. 2024 Apr 1;15(1):93. doi: 10.1186/s13287-024-03701-8. PMID: 38561834; PMCID: PMC10985951.
  25. Abdullah KM, Sharma G, Takkar S, Kaushal JB, Pothuraju R, Chakravarti B, Batra SK, Siddiqui JA. α-lipoic acid modulates prostate cancer cell growth and bone cell differentiation. Sci Rep. 2024 Feb 22;14(1):4404. doi: 10.1038/s41598-024-54479-x. PMID: 38388663; PMCID: PMC10884017.
  26. Abdullah KM, Kaushal JB, Takkar S, Sharma G, Alsafwani ZW, Pothuraju R, Batra SK, Siddiqui JA. Copper metabolism and cuproptosis in human malignancies: Unraveling the complex interplay for therapeutic insights. Heliyon. 2024 Mar 7;10(5):e27496. doi: 10.1016/j.heliyon.2024.e27496. PMID: 38486750; PMCID: PMC10938126.
  27. Krishna S, Fasaludeen A, Jose M, Banerjee M, Sundaram S, Radhakrishnan A, Menon RN. Impact of variant subtype on electro-clinical phenotype of Dravet syndrome- a South Indian cohort study. Seizure. 2024 Feb;115:81-86. doi: 10.1016/j.seizure.2024.01.004. Epub 2024 Jan 14. PMID: 38232648.
  28. Asha S, Kattupalli D, Vijayanathan M, Soniya EV. Identification of nitric oxide mediated defense signaling and its microRNA mediated regulation during Phytophthora capsici infection in black pepper. Physiol Mol Biol Plants. 2024 Jan;30(1):33-47. doi: 10.1007/s12298-024-01414-z. Epub 2024 Feb 11. PMID: 38435849; PMCID: PMC10901764.
  29. Rajagopalan K, Selvan Christyraj JD, Chelladurai KS, Kalimuthu K, Das P, Chandrasekar M, Balamurugan N, Murugan K. Understanding the molecular mechanism of regeneration through apoptosis-induced compensatory proliferation studies - updates and future aspects. Apoptosis. 2024 Apr 6. doi: 10.1007/s10495-024-01958-1. Epub ahead of print. PMID: 38581530.
  30. Rossan Mathews MG, Subramaniam R, Venkatachalam S, Selvan Christyraj JRS, Yesudhason BV, Kalimuthu K, Mohan M, Selvan Christyraj JD. Biochemical and functional characterization of heat-inactivated coelomic fluid from earthworms as a potential alternative for fetal bovine serum in animal cell culture. Sci Rep. 2024 Mar 7;14(1):5606. doi: 10.1038/s41598-024-56169-0. PMID: 38453984; PMCID: PMC10920628.
  31. Debparna Nandy, Pallavi Varghese, Mayur Shirude, Anjali Devarajan, Debasree Dutta, Abstract 1776 Nuclear APLF in the regulation of breast cancer metastasis, Journal of Biological Chemistry,Volume 300, Issue 3, Supplement,2024,106688,ISSN 0021-9258,https://doi.org/10.1016/j.jbc.2024.106688.
  32. Kumar TP, Gireesh-Babu P, Vasudevan D, Pavan-Kumar A, Chaudhari A. Characterization of Kiss/Kissr system and expression profiling through developmental stages indicate kiss1 to be the active isotype in Clarias magur. Fish Physiol Biochem. 2024 Apr 22. doi: 10.1007/s10695-024-01343-4. Epub ahead of print. PMID: 38647980.
  33. Santhoshkumar R, Hima Parvathy A, Soniya EV. Biocompatible silver nanoparticles as nanopriming mediators for improved rice germination and root growth: A transcriptomic perspective. Plant Physiol Biochem. 2024 Apr 18;210:108645. doi: 10.1016/j.plaphy.2024.108645. Epub ahead of print. PMID: 38663266.
  34. B.J. Sreelakshmi, C.L. Karthika, S. Ahalya, S.R. Kalpana, C.C. Kartha, S. Sumi,Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling.European Journal of Cell BiologyVolume 103, Issue 2,2024,151420,ISSN 0171-9335,https://doi.org/10.1016/j.ejcb.2024.151420.
  35. Modak A, Mishra SR, Awasthi M, Aravind A, Singh S, Sreekumar E. Fingolimod (FTY720), an FDA-approved sphingosine 1-phosphate (S1P) receptor agonist, restores endothelial hyperpermeability in cellular and animal models of dengue virus serotype 2 infection. IUBMB Life. 2024 May;76(5):267-285. doi: 10.1002/iub.2795. Epub 2023 Nov 30. PMID: 38031996.
  36. Remadevi V, Jaikumar VS, Vini R, Krishnendhu B, Azeez JM, Sundaram S, Sreeja S. Urolithin A, induces apoptosis and autophagy crosstalk in Oral Squamous Cell Carcinoma via mTOR /AKT/ERK1/2 pathway. Phytomedicine. 2024 May 6;130:155721. doi: 10.1016/j.phymed.2024.155721. Epub ahead of print. PMID: 38788395.
  37. Vijayanathan M, Vadakkepat AK, Mahendran KR, Sharaf A, Frandsen KEH, Bandyopadhyay D, Pillai MR, Soniya EV. Structural and mechanistic insights into Quinolone Synthase to address its functional promiscuity. Commun Biol. 2024 May 14;7(1):566. doi: 10.1038/s42003-024-06152-2. PMID: 38745065; PMCID: PMC11093982.
  38. Ivan N Bolotov, Jyotish Sonowal, Devid Kardong, Rajeev Pasupuleti, Nalluri V Subba Rao, Suresh Kumar Unnikrishnan, Mikhail Y Gofarov, Alexander V Kondakov, Ekaterina S Konopleva, Artem A Lyubas, Ilya V Vikhrev. Discovery of an endemism hotspot of freshwater mussels (Bivalvia: Unionidae) in Assam, with a description of two new genera. The Zoological Journal of the Linnean Society https://doi.org/10.1093/zoolinnean/zlae052
  39. Devika Vikraman, Bibhab Bandhu Majumdar, Sharavanakkumar SK, Conrad Weichbrodt, Niels Fertig, Mathias Winterhalter, Jagannath Mondal and Kozhinjampara R. Mahendran. Conformational flexibility driving charge-selective substrate translocation across a bacterial transporter. chemical science https://doi.org/10.1039/D4SC00345D
  40. Alfiya Fasaludeen, Amy McTague, Manna Jose, Moinak Banerjee, Soumya Sundaram, U.K. Madhusoodanan, Ashalatha Radhakrishnan, Ramshekhar N. Menon. Genetic variant interpretation for the neurologist - A pragmatic approach in the next-generation sequencing era in childhood epilepsy. Epilepsy Research, 201, 2024,107341
  41. Jose M, Fasaludeen A, Pavuluri H, Rudrabhatla PK, Chandrasekharan SV, Jose J, Banerjee M, Sundaram S, Radhakrishnan A, Menon RN. Challenges in genetic testing for metabolic causes of developmental epileptic encephalopathy- relevance of genotype-phenotype correlations. Seizure. 2024 Apr;117:307-308. doi: 10.1016/j.seizure.2024.02.012. Epub 2024 Feb 20. PMID: 38402011.
  42. Parte S, Pothuraju R, Kumavath R, Bhatia R, Nimmakayala RK, Gautam S. Editorial: Altered metabolic traits in gastrointestinal tract cancers. Front Endocrinol (Lausanne). 2024 May 22;15:1390877. doi: 10.3389/fendo.2024.1390877. PMID: 38841308; PMCID: PMC11150827.
  43. Remadevi V, Jaikumar VS, Vini R, Krishnendhu B, Azeez JM, Sundaram S, Sreeja S. Urolithin A, induces apoptosis and autophagy crosstalk in Oral Squamous Cell Carcinoma via mTOR /AKT/ERK1/2 pathway. Phytomedicine. 2024 Jul 25;130:155721. doi: 10.1016/j.phymed.2024.155721. Epub 2024 May 6. PMID: 38788395.
  44. Krishnan R S, Firzan Ca N, Mahendran KR. Functionally Active Synthetic a-Helical Pores. Acc Chem Res. 2024 Jun 14. doi: 10.1021/acs.accounts.4c00101. Epub ahead of print. PMID: 38875523.
  45. Sruthy Manuraj Rajam, Pallavi Chinnu Varghese, Mayur Balkrishna Shirude, Khaja Mohieddin Syed, Anjali Devarajan, Kathiresan Natarajan, Debasree Dutta. Kinase activity of histone chaperone APLF maintains steady state of centrosomes in mouse embryonic stem cells. European Journal of Cell Biology28 June 2024 https://doi.org/10.1016/j.ejcb.2024.151439
  46. Rashmi Sukumaran , Achuthsankar S. Nair, Moinak Banerjee.Ethnic and region-specific genetic risk variants of stroke and its comorbid conditions can define the variations in the burden of stroke and its phenotypic traits eLife 10 June 2024, https://doi.org/10.7554/eLife.94088.2

Book Chapter

  1. Vandana Sharma; Victor Samuel; Chenicheri K Keerthana; Praveen Archana; Shifana Chembothumparambil Sadiq; Mundanattu Swetha; Tennyson Prakash Rayginia, Sreekumar Usha Devi Aiswarya; Kalimuthu Kalishwaralal. Role of plant-derived extracellular nanovesicles in triggering innate immune response against plant pathogens. Nanotechnology in Plant Health 256 - 267
  2. Mayur Balkrishna Shirude & Debasree Dutta. Histone Chaperones in Cancer. Handbook of Oncobiology: From Basic to Clinical Sciences 845-864

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