Profile

Our laboratory is focused on the world's top infectious killer, Mycobacterium tuberculosis, the causative agent of tuberculosis. This bacterium has begun to show broad resistance to a large number of anti-tuberculosis drugs, becoming one of the greatest challenges for public health worldwide. We investigate the fundamental mechanisms by which the bacteria evade the host immune system and create a protective niche in the human body. We use cutting-edge technologies to study host-pathogen interaction.
We also study the pathogenesis of Chlamydia infections, the most common cause of sexually transmitted infections. As an obligate intracellular parasite, Chlamydia metabolically reprograms host cells to live an intracellular lifestyle. My group focuses on the host-pathogen interaction and how the pathogen evades the host immune system.