α-Fodrin is required for the organization of functional microtubules during mitosis.

Rohith Kumar Nellikka, Jamuna S Sreeja, Dhrishya Dharmapal, Rince John,Augusta Monteiro, Joana Catarina Macedo, Carlos Conde, Elsa Logarinho, Claudio E. Sunkel and Suparna Sengupta (2019)

Binding of alpha-fodrin to gamma-tubulin accounts for its role in the inhibition of microtubule nucleation.

Jamuna S. Sreeja, Rohith Kumar Nellikka, Rince John, Krishnankutty C. Sivakumar, Easwaran Sreekumar and Suparna Sengupta (2019)
FEBS Letters     593, 1154-1165 doi:10.1002/1873-3468.13425

ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells.

ReshmaThamkachy, Rohith Kumar, K. N. Rajasekharan and Suparna Sengupta (2016)
Molecular Cancer     15:22

6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death.

Anasuya Ray, SmretiVasudevan, SuparnaSengupta (2015)
PLoS One     10(9): e0137614.

Diaminothiazoles Evade Multidrug Resistance in Cancer Cells and Xenograft Tumour Models and Develop Transient Specific Resistance: Understanding the Basis of Broad-Spectrum vs Specific Resistance.

SmretiVasudevan, Sannu Ann Thomas, Krishnankutty C. Sivakumar, Reena J. Komalam, Keerthi V. Sreerekha, Kallikat N. Rajasekharan and SuparnaSengupta* (2015)
Carcinogenesis36     36(8):883-93

Reversible Action of Diaminothiazoles in Cancer Cells is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics.

Nisha E Thomas, ReshmaThamkachy, Krishnankutty C. Shivakumar, Sreedevi K.J., Xavier Lieben Louis, Sannu A. Thomas, Rohith Kumar, Kallikat N. Rajasekharan, Lynne Cassimeris & SuparnaSengupta* (2014)
Molecular Cancer Therapeutics     13, 179 - 189

A regioselective multicomponent protocol for the synthesis of novel bioactive 4-hydroxyquinolin-2(1H)-one grafted monospiropyrrolidine and thiapyrrolizidine hybrids.

MathanSankaran, ChokkalingamUvarani, KumarasamyChandraprakash, Swathi U. Lekshmi, Sengupta Suparna, James Platts, PalathuraiSubramaniam Mohan (2014)
Molecular Diversity     18(2):269-83

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