EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine glycine biosynthesis.

Nirmalya Sen, Allison M. Cross, Philip L. Lorenzi, Javed Khan, Berkley E. Gryder, Suntae Kim, Natasha J. Caplen(2018)
Molecular Carcinogenesis     doi.org/10.1002/mc.22849.

PRKDC, the catalytic subunit of DNA-dependent protein kinase, regulates EWS-FLI1 stability.[Under communication]

Nirmalya Sen, Katelyn Ludwig , Guillermo Rangel-Rivera , Suntae Kim , Konrad Huppi , Lisa Jenkins , Jennifer Dwyer , Shelley Hoover , Lee Helman , R. Mark Simpson , Arnulfo Mendoza , Amanda Hummon, Natasha J. Caplen.
Cancer Cell    

PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.

Berkley E. Gryder , Marielle E. Yohe , Nirmalya Sen , Hsien-Chao Chou , Xiaohu Zhang , Joana Marques , Marco Watchte , Beat Schaefer , Alberto Gualtieri , Silvia Pomella , Rossella Rota , Young K. Song , Abigail Cleveland , Xinyu Wen , Mr. Sivasish Sindiri , Jun S. Wei , Frederic G. Barr , Rajarshi Guha , Madhu Lal-Nag , Marc Ferrer , Thorkell Andresson , Jack F. Shern , Keji Zhao , Craig J. Thomas, Javed Khan. (2017)
Cancer Discovery     Volume 7, Issue 8, p884-899

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as Vulnerability in Ewing Sarcoma.

Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O'Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, and Natasha J. Caplen. (2016)
Cell Reports     Volume 14, Issue 3, p598-610

Role of MTA1 in cancer progression and metastasis.

Nirmalya Sen, Gui Bin, Rakesh Kumar. (2014)
Cancer Metastasis Rev.     33(4):879-89.

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