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K. Santhosh Kumar, Ph.D.
Scientist E-II |
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Peer reviewed
Peer reviewed
- Reshmy, V., Preeji, V., Parvin, A., Santhoshkumar, K. and George, S. (2011), Three novel antimicrobial peptides from the skin of the Indian bronzed frog Hylarana temporalis (Anura: Ranidae). Journal of Peptide Science, 17: 342–347. doi: 10.1002/psc.1363.
- Reshmy V, Kumar K.S and George S 2011. Full Length cDNA derived Novel Peptides belonging to Esculentin Family from Skin of Indian Bronzed Frog Hylarana temporalis. Research Journal of Biotechnology 6 (1), 71-74
- Nair. A, Kumar.K.S, George S., Sujith V. G., Meng-Hua Li., Erica H. Leder & Juha Merila. 2011. Sixty-two new microsatellite markers for an endemic frog Indirana beddomii from the Western Ghats biodiversity hotspot. Conservation Genet Resour, 3:167–171
- Reshmy, V. Preeji, A. Parvin, K. Santhoshkumar and George.S. 2010.Molecular Cloning of a Novel Bradykinin-Related Peptide from the Skin of Indian Bronzed FrogHylarana temporalis. Genomic insights 3: 23–28
- Meenakshi K., Suraj T., Bhagwati S S., Sujith V G., Santhoshkumar K., George S.. 2010. Molecular resolution of four Species Fejervarya from Western Ghats (India) with their intrageneric phylogeny based on COI, Cyt B, 12S and 16S rRNA Genes. Asian J. Exp. Biol. Sci 194:782-786
- M. K. Jacob, S. Leena and K. S. Kumar*., Biotherapeutic Synthesis on Novel Cross-Linked Beads with ‘‘Spatially Tunable’’ and ‘‘Isolated’’ Functional Sites Biopolymer (Peptide Science) 90, 2008, 512-525.
- Dongxiang Liu, Navid Madani, Ying Li, Rong Cao, Won-Tak Choi, Sameer P. Kawatkar, Mi Youn Lim, Santosh Kumar, Chang-Zhi Dong, Jun Wang, Julie D. Russell, Caroline R. Lefebure, Jing An, Scott Wilson, Yi-Gui Gao, Luke A. Pallansch, Joseph G. Sodroski, and Ziwei Huang Crystal Structure and Structural Mechanism of a Novel Anti-Human Immunodeficiency Virus and D-Amino Acid-Containing Chemokine J. Virol. 2007 81: 11489-11498.
- Ying Li, Dongxiang Liu, Rong Cao, Santosh Kumar, Changzhi Dong, Jing An, Scott R. Wilson, Yi-Gui Gao, Ziwei Huang. Crystal structure of chemically synthesized vMIP-II Proteins: Structure, Function, and Bioinformatics 67, 2007, 243-246
- Won-Tak Choi, Marcus Kaul, Santosh Kumar, Jun Wang, I. M. Krishna Kumar, Chang-Zhi Dong, Jing An, Stuart A. Lipton, and Ziwei Huang. Neuronal Apoptotic Signaling Pathways Probed and Intervened by Synthetically and Modularly Modified (SMM) Chemokines J. Biol. Chem..2007; 282: 7154-7163.
- Jun Wang, Santhosh Kumar, Won-Tak Choi, Changzhi Dong and Ziwei Huang. Design and Synthesis of Novel Chemokine Analogs Derived from vMIP-II, Protein & Pept Lett, 2006, 13 499-501.
- Santosh Kumar, Won-Tak Choi, Chang-Zhi Dong, Navid Madani, Shaomin Tian, Dongxiang Liu, Youli Wang, James Pesavento, Jun Wang, Xuejun Fan, Jian Yuan, Wayne R. Fritzsche, Jing An, Joseph G. Sodroski, Douglas D. Richman and Ziwei Huang. SMM-Chemokines: A Class of Unnatural Synthetic Molecules as Chemical Probes of Chemokine Receptor Biology and Leads for Therapeutic Development. Chem Biol 2006, 13, 69-79.
- C, Z. Dong., Santosh Kumar., W. T. Choi., N, Madani., S. Tian., J. An., J, G. Sodroski and Z. Huang Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand. J Med Chem. 2005, 48(25):7923-7924.
- W. T. Choi., S. Tian., C, Z. Dong., Santosh Kumar., D. Liu., N, Madani., J. An., J, G. Sodroski and Z. Huang Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors. J Virol., 2005, 24, 15398-15404.
- M. Mori., D. Liu., Santosh Kumar and Z. Huang NMR structures of anti-HIV D-peptides derived from the N-terminus of viral chemokine vMIP-II. Biochem Biophys Res Commun. 2005, 335(3), 651-658.
- G. S. Vinod Kumar and K. Santhosh Kumar, Immobilization of catalase on a Novel Polymer Support, CLPSER: Role of the Macromolecular Matrix on Enzyme Activity. J Appl. Pol. Sci., 2005, 97: 8-19.
- G. S. Vinod Kumar., S. Leena and K. Santhosh Kumar Synthesis of a shark repellent peptide toxin, pardaxin (16-33) on a highly flexible polymer support: CLPSER. Protein and Peptide Letters, 2004, 11: 1-10.
- Sasikumar, P. G., Kumar, K. S. & Rajasekharan Pillai, V. N.R A novel chemically and mechanically stable glycerol-based crosslinked polystyrene support for polypeptide synthesis: A comparative study with Merrifield resin. J Appl. Pol. Sci. 92, 288 - 294 (2004).
- Sasikumar, P. G., Kumar, K. S. & Rajasekharan Pillai, V. N.R Tri(propylene glycol) glycerolate diacrylate cross-linked polystyrene: a new resin support for solid-phase peptide synthesis. J Pept Res 62, 1-10 (2003).
- Sasikumar, P. G., Kumar, K. S. & Pillai, V. N. R Synthesis of retro acyl carrier protein (74-65) fragment on a new glycerol based polystyrene support. Protein Pept Lett 10, 427-33 (2003).
- Sasikumar, P. G., Kumar, K. S., Arunan, C. & Pillai.V.N, R. Synthesis and optimization of tri(propylene glycol) glycerolate diacrylate cross-linked polystyrene resin in polypeptide synthesis: Role of macromolecular support in solid phase peptide synthesis. Journal of Chemical Society, Perkin Transactions. 1, 2886-2895 (2002).
- Mayadevi, M., Praseeda, M., Kumar, K. S. & Omkumar, R. V. Sequence determinants on the NR2A and NR2B subunits of NMDA receptor responsible for specificity of phosphorylation by CaMKII. Biochim Biophys Acta 1598, 40-5 (2002).
- Roice, M., Kumar, K. S. & Pillai, V. N.R Chemical synthesis of NS-1 region of hepatitis C-viral polyprotein fragments: a comparison of PS-BDODMA resin and Merrifield resin. Protein Pept Lett 9, 245-52 (2002).
- Roice, M., Suma, G., Kumar, K. S. & Pillai, V. N. R Synthesis of esculentin-1 antibacterial peptide fragments on 1,4-butanediol dimethacrylate cross-linked polystyrene support. J Protein Chem 20, 25-32 (2001).
- Leena, S. & Kumar, K. S. Syntheses, characterization and application of cross-linked polystyrene-ethyleneglycol acrylate resin (CLPSER) as a novel polymer support for polypeptide syntheses. J Pept Res 58, 117-28 (2001).
- Kumar, K. S. Roice, M. Sasikumar, P. G. Poduri, C. D. Sugunan, V. S. Rajasekharan Pillai, V. N. Das, & M. R Syntheses of immunodominant peptide regions of hepatitis C viral pathogens using PS-BDODMA resin: a single peptide derived from the conserved domain (E2/NS1) was highly effective in detecting anti-HCV antibodies. J Pept Res 57, 140-50 (2001).
- Poduri, I. Cd Khanna, A. Khundmiri, S. J. Khaja, M. N. Kumar, K. S. Sugunan, V. S. Habibullah, C. M.& Das, M. R. Predominance of antibodies to hepatitis C virus envelope proteins in various disease statuses of hepatitis C. Acta Virol 45, 1-6 (2001).
- Roice, M., Kumar, K. S. & Pillai, V. N. R. Photocleavable 2-nitrobenzylamino anchored polystyrene-butanediol dimethacrylate supports for the synthesis of protected peptides, peptide amides and peptide N-alkyl amides. Tetrahedron 57, 3151-3158 (2001).
- Kumar, K. S., Roice, M. & Pillai.V.N, R. Synthesis of Alzheimer's ?-amyloid peptide fragment (33-42) on a new chemically inert PS-BDODMA support. Protein and Peptide Letters 7, 151-158 (2000).
- Kumar, K. S., Rajasekharan Pillai, V. N. & Das, M. R. Syntheses of four peptides from the immunodominant region of hepatitis C viral pathogens using PS-TTEGDA support for the investigation of HCV infection in human blood. J Pept Res 56, 88-96 (2000).
- Roice, M., Kumar, K. S. & Pillai, V. N. R. Optimization in peptide synthetic conditions of 1,4-butanediol dimethacrylate cross-linked polystyrene resin and its efficiency in solid phase peptide synthesis. Tetrahedron 56, 3725-3734 (2000).
- Roice, M., Kumar, K. S. & Pillai, V. N. R. Synthesis, characterization and application of butanediol dimethacrylate crosslinked polystyrene: A Flexible Support Gel Phase Peptide Synthesis. Macromolecules 32, 8807-8815 (1999).
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