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Ruby John Anto, Ph.D.
Scientist E-II
Tel : +91-471-2529473
Email : rjanto@rgcb.res.in

 

GRANTS


Sl. No

Title of Project

Funding Agency

Duration (From-To)

Total Approved Cost of theProject (In Rs.)
1 Isolation and identification of anticancer principle from Mistletoes(Viscum album) growing on various host trees ICMR, Govt. of India 2006-2009 10,17,600
2 Development of High Specific and High Affinity monoclonal antibody against human IgM. TreeLand Biotech 2006-2009 32,38,320/-
3 Isolation and identification of anticancer principle from the indigenous medicinal plant, Wrightia tinctoria CSIR, Govt. of India 2006-2009 12,72600/-
4 Antineoplastic molecules associated with bacteria from entomopathogenic nematodes Co-PI STEC, Govt of Kerala 2007-2010 11,25300/-
5 Novel polymer nanoparticle based drug releasing systems for improving the efficacy of drug administration in cancer chemotherapy. Co-PI DBT, Govt. of India 2008-2011 41,53,000


Completed Research Projects

Sl. No. Title of Project Funding Agency Duration From To

Total Approved Cost of the Project (In Rs.)


Output Publications/Patents
1 Synergistic effect of Taxol and curcumin in inducing apoptosis of cancer cells STEC, Govt. of Kerala 2003-2006 6,07,000 Bava et al 2005, J. Biol. Chem., 280: 6301 - 6308
2

Sensitization of conventional chemotherapeutic drugs using non-toxic chemo preventives


DBT, Govt.of India 2003-2008 Program support to RGCB Bava et al 2005, J. Biol. Chem., 280: 6301 - 6308 Bava et al 2010 Int J Biochem Cell Biol, 43, 331-341. Sreekanth et al 2011, Oncogene, DOI:10.1038/onc.2011.23.
3 Potential Role of curcumin in regulating the effects induced by the major carcinogens in cigarette smoke, such as nicotine, NNK and B(a)P in normal and cancerous lung cells. DST, Govt. of India STNo:SR/SO/HS-49/2002 2005-2008 19,97,000 Puliyappadamba et al 2010, Mol Cancer, Highly Accessed. In press DOI: 10.1186/1476-4598-9-220.
4 Isolation and identification of anticancer principle from Mistletoes(Viscum album) growing on various host trees ICMR, Govt. of India 2006-2009 10,17,600 Manuscript under communication
5 Development of High Specific and High Affinity monoclonal antibody against human IgM. TreeLand Biotech (Industrial project) 2006-2009 32,38,320/- Developed monoclonal antibody against human IgM
6 Isolation and identification of anticancer principle from the indigenous medicinal plant, Wrightia tinctoria CSIR, Govt. of India 2006-2009 12,72600/-

Patent Filed on: 20.09.2010, Patent Application No. 2743/CHE/2010 Manuscript under communication

7 Antineoplastic molecules associated with bacteria from entomopathogenic nematodes Co-PI STEC, Govt of Kerala 2007-2010 11,25300/- Patent filing in progress


Ongoing Projects

Sl. No.

Title of Project Funding Agency Duration From To

Total Approved Cost of the Project (In Rs.)


Output Publications/Patents
1 Novel polymer nanoparticle based drug releasing systems for improving the efficacy of drug administration in cancer chemotherapy.( Co-PI) DBT, Govt. of India 2008-2011 41,53,000 Manuscript under communication


COLLABORATIONS

  • Dr. Bharat Aggarwal, M.D Anderson Cancer Center, Houston, Texas, USA- Role of TNF- family members on proliferation and apoptosis
  • Dr.M.Sreerama Moorthy, Indian Institute of Chemical technology, Hyderabad – Identification of new of anticancer drugs

  • Dr. Daisy Philip, Department of Physics, Mar Evanios College, Thiruvananthapuram: Spectroscopic analysis for the structure elucidation of compounds
  • Dr. C Mohandas, CTCRI, Thiruvananthapuram- STEC funded project, Antineoplastic molecules associated with bacteria from entomopathogenic nematodes
  • Dr. Bala Nambisan CTCRI, Thiruvananthapuram- STEC funded project, Antineoplastic molecules associated with bacteria from entomopathogenic nematodes