Papers

1. Thasni KA, Ratheeshkumar T, Rojini G, Sivakumar KC, Rakesh Sathish Nair, Srinivas G, Asoke Banerji, Veena Somasundaram, Priya Srinivas. Structure activity relationship of Plumbagin in BRCA1 related Cancer Cells. Accepted Molecular Carcinogenesis, 2012.
2. Priya PS, Suboj Babykutty, Deepak Roshan V G, Rakesh S Nair, Priya Srinivas, Srinivas Gopala. Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-?B. Accepted, European Journal of Pharmaceutical Sciences, 2012.
3. Priya Prasanna Sathiadevan, Suboj Babykutty, Priya Srinivas, Srinivas Gopala. Aloe emodin induces G2/M cell cycle arrest, and apoptosis via activation of caspase- 6 in human colon cancer cells. Pharmacology (Accepted 2011).
4. Priya Srinivas, Chitta Ranjan Patra, Santanu Bhattacharya and Debabrata Mukhopadhyay. Cytotoxicity and ROS generating capacity of naphthaquinones is quenched when conjugated with gold nanoparticles. International J of Nanomedicine, 2011:6 2113–2122
5. Suboj Babykutty, Priya P.S., Nandini R.J., M.A. Suresh Kumar, Mangalam S. Nair, Priya Srinivas and Srinivas Gopala. Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-?B in colon cancer cells. Molecular Carcinogenesis. 15 JUN 2011, DOI: 10.1002/mc.20812
6. Priya Srinivas, Veena Somasundaram, Rakesh S, Thasni KA, Premakumari P, Srinivas G. Multifaceted approach with a single drug for BRCA1 defective cancers. Current Medicinal Chemistry, Special Issue, (Abstract), 2011, p 107.
7. Veena Somasundaram & Priya Srinivas, Insights into the targeted elimination of BRCA1 defective cancer stem cells, Medicinal Research Reviews, September, 2010, DOI 10.1002/med.20229
8. Suboj Babykutty, Jose Padikkala. Priya Prasanna Sathiadevan, Vinod Vijayakurup, Thasni Karedath Abdul Azis, Priya Srinivas, Srinivas Gopala. Apoptosis Induction of Centella Asiatica on Human Breast Cancer Cells. Afr.J.Trad.CAM, 6 (1): 2009, pp. 9-16, 2009
9. Priya Prasanna Sathiadevan, Suboj Babykutty, Vinod Vijayakurup, Padmakrishnan. C. J, Priya Srinivas, Gopal Srinivas. Aloe emodin, a versatile anthraquinone targeting multiple facets (apoptosis, metstasis, angiogenesis) of cancer progression. (Abstract) European Journal of Cancer (Supplements), Vol 7 No 2, September 2009, Page 95.
10. Priya Srinivas, Rakesh S Nair, Prathapachandra Kurup M.R and Mini Kuriakose. Molecular trail for the action of a metal based drug in HPV positive cervical cancer cells. (Abstract), Cancer Prevention Research: November 2008; Volume 1, Issue 7, Supplement. doi: 10.1158/1940-6207.PREV-08-A71
11. Karedath Abdul Aziz Thasni, Gopakumaran Rojini, S. Nair Rakesh, Thankappan Ratheeshkumar, Mani Shankar Babu, Gopala Srinivas, Asoke Banerji, Priya Srinivas. Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-gene-1 (BRCA1) status. European Journal of Pharmacology, Vol 588, 2-3, p 158-164, 2008. (http://dx.doi.org/10.1016/j.ejphar.2008.04.041).
12. Thasni KA, Rakesh S, Rojini G, Ratheeshkumar T, Srinivas G, Priya Srinivas. Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents. Ann Oncol 2008; 19: 4; 696-705. doi:10.1093/annonc/mdm557
13. Sreekala Nair, Raghu Ram K Nair, Priya Srinivas, Gopal Srinivas, and M Radhakrishna Pillai. Radiosensitizing effect of plumbagin in cervical cancer cells is through the modulation of apoptotic pathway. Molecular Carcinogenesis, 47, (1), 22-33, 2008.
14. Thasni K A, Rakesh S Nair, Rojini G, Ratheesh kumar T, Srinivas Gopal, Asoke Banerjj, Priya Srinivas Naphthaquinones - Promising anticancer agents against breast and ovarian cancer treatment. (Abstract) - Breast Cancer Research and Treatment, Vol 106, Supplement 1, December 2007.
15. Thasni K A, Rojini G, Srinivas G, Asoke Banerji, Priya Srinivas. Molecular mechanism of action of plumbagin in BRCA1 blocked ovarian cancer cell line by suppression subtractive hybridization and micro array. (Abstract) Annals of Oncology, Volume 18, Supplement 4, May 2007.
16. Priya Srinivas, Thasni K A, Rakesh S Nair, Rojini G, Ratheeshkumar T, Asoke Banerji, Srinivas G. Targeted anticancer therapy for BRCA1 blocked estrogen receptor positive ovarian cancers. (Abstract) Annals of Oncology, Volume 18, Supplement 4, May 2007.
17. Gopal Srinivas, Suboj Babykutty, Priya Prasanna Sathiadevan, Priya Srinivas. Molecular Mechanism of Emodin Action: Transition from Laxative Ingredient to an Antitumor Agent. Medicinal Research Reviews, 27 (5), 591-608, 2007.
18. T.R. Cibin, G. Srinivas, D. Gayathri Devi, Priya Srinivas and Annie Abraham. Antioxidant and Antiproliferative Effects of Flavonoids from Emilia sonchifolia Linn on Human Cancer Cells. International Journal of Pharmacology 2 (5): 520-524, 2006.
19. Priya Srinivas, Gokul Gopinath, Asoke Banerji, Abhilash Dinakar, Gopal Srinivas. Plumbagin induces reactive oxygen species mediated apoptosis in human cervical cancer cells. Mol. Carcinogenesis, 39(1): 15-25, 2004.
20. Gopal Srinivas, Lois A Annab, Gokul Gopinath, Asoke Banerji, Priya Srinivas. Antisense blocking of BRCA1 enhances the sensitivity to plumbagin but not tamoxifen in BG-1 ovarian cancer cells. Mol Carcinogenesis, 40; 201-211, 2004. http://onlinelibrary.wiley.com/doi/10.1002/mc.10164/pdf.
21. Srinivas G, Anto RJ, Srinivas P, Vidhyalakshmi S, Senan VP, Karunagaran D. Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9. Eur J Pharmacol 473(2-3):117-125, 2003.
22. Priya Srinivas, E Abraham, I Ahamed, M Madhavan, N.R.Vijayalakshmi, M K Nair, P Balaram. Apoptotic index: use in predicting recurrence in breast cancer patients. J Exp Clin Cancer Res. 21(2), 233-238, 2002.
23. Priya Srinivas, Maya Madhavan, Iqbal Ahamed, Elizabeth Abraham, N.R. Vijayalakshmi, Prabha Balaram. Nm23H1 and p53 proteins are differentially correlated to metastasis in breast carcinoma. Neoplasma, 49, (4), 225-230, 2002.
24. Maya Madhavan, Priya Srinivas, Elizabeth Abraham, Iqbal Ahmed, N.R. Vijayalakshmi and Prabha Balaram. Down Regulation of Endothelial Adhesion Molecules in Node Positive Breast Cancer: Possible Failure of Host Defense Mechanism. Pathology Oncology Research 8(2), 125–128, 2002.
25. Maya Madhavan, Priya Srinivas, Elizabeth Abraham, Iqbal Ahmed, N.R. Vijayalakshmi and Prabha Balaram. Cadherins as Predictive Markers of Nodal Metastasis in Breast Cancer. Mod Pathol 4(5):423–427, 2001.
26. Priya Srinivas, Prabha Balaram, Maya Madhavan, Iqbal Ahamed, Elizabeth Abraham, N.R. Vijayalakshmi. Nm23H1 – expression and relation to prognosis in breast cancers. Amala Cancer Bullettin, Vol. 21, 146-150, 2001.
27. Maya Madhavan, Prabha Balaram, Elizabeth Abraham, Iqbal Ahmed, N.R. Vijayalakshmi and Priya Srinivas. Cadherins: Prognostic implications in Breast Carcinoma. Amala Cancer Bullettin, Vol. 21, 140-145, 2001.